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Pigp Gene Detail
Summary
  • Symbol
    Pigp
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class P
  • Synonyms
    Dcrc, Dscr5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860433
    NCBI Gene: 56176
  • Gene Overview
    MyGene.info: PIGP
Location & Maps
more
  • Sequence Map
    Chr16:94358763-94371015 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12253 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 55.18 cM, cytoband C3-C4
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PIGP, phosphatidylinositol glycan anchor biosynthesis class P
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PIGP, phosphatidylinositol glycan anchor biosynthesis class P
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DCRC, DCRC-S, DSCR5, DSRC, PIG-P
  • Links
    NCBI Gene ID: 51227
    neXtProt AC: NX_P57054

  • Chr Location
    21q22.2; chr21:37065364-37073158 (-)  GRCh38.p2

Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from multigenic genotypes
    27 phenotype references
  • All Mutations and Alleles
    18
  • Gene trapped
    6
  • Targeted
    10
  • Transgenic
    2
  • Genomic Mutations
    8 involving Pigp
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019883 VEGA Gene Model | MGI Sequence Detail 12253 C57BL/6J ±  kb
transcript OTTMUST00000047404 VEGA | MGI Sequence Detail 912 Not Applicable  
polypeptide OTTMUSP00000021417 VEGA | MGI Sequence Detail 205 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    90 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000012703 phosphatidylinositol N-acetylglucosaminyltransferase subunit P
  • EC
  • InterPro Domains
    IPR031952 KH-like RNA-binding domain
    IPR016542 Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit
    IPR013717 PIG-P
Molecular
Reagents
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  • All nucleic 53
    cDNA 51
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Diseases 3
    Gene Ontology 4
    Phenotypes 27
  • Earliest
    J:138284 Watanabe R, et al., Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2. EMBO J. 2000 Aug 15;19(16):4402-11
  • Latest
    J:180201 Liu C, et al., Genetic analysis of Down syndrome-associated heart defects in mice. Hum Genet. 2011 Nov;130(5):623-32

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory