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Nagk
Gene Detail
Symbol

Name
ID
Nagk
N-acetylglucosamine kinase
MGI:1860418
Synonyms
GlcNAc kinase
Feature Type
protein coding gene
Genetic Map
Chromosome 6
35.96 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:83794982-83803420 bp, + strand
From VEGA annotation of GRCm38

  8439 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9720  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NAGK
Gene Tree: Nagk

Human
homologs
NAGK, N-acetylglucosamine kinase
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55577
neXtProt AC: NX_Q9UJ70

Human Synonyms: GNK, HSA242910

Human Chr (Location): 2p13.3; chr2:71068241-71078868 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(2) Spontaneous(1) Targeted(7)
Genomic Mutations involving Nagk (1)
Incidental mutations (data from Mutagenetix , APF )
 
A gene trap insertion into an intron of this gene results in no obvious phenotype.
 
Interactions
Nagk interacts with 141 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process carbohydrate phosphorylation, N-acetylglucosamine metabolic process, ...
Component extracellular exosome
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
Northern blot 12
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase nagk    NEW 
Molecular
reagents
All nucleic(8) cDNA(7) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000023757 (Evidence)
Ensembl Gene Model ENSMUSG00000034744 (Evidence)
Entrez Gene 56174 (Evidence)
DFCI TC1681289, TC1611040, TC1580187, TC1616381
NIA Mouse Gene Index U007088
EC 2.7.1.59
Consensus CDS Project CCDS20286.1
International Mouse Phenotyping Consortium Status Nagk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023757 VEGA Gene Model | MGI Sequence Detail 8439 C57BL/6J ±  kb
transcript OTTMUST00000058044 VEGA | MGI Sequence Detail 1323 Not Applicable 
polypeptide OTTMUSP00000028071 VEGA | MGI Sequence Detail 361 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(12) UniProt(4)
Polymorphisms
SNPs within 2kb(66 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002731 ATPase, BadF/BadG/BcrA/BcrD type
Protein Ontology PR:000010960 N-acetyl-D-glucosamine kinase
References
(Earliest) J:62543 Hinderlich S, et al., Molecular cloning and characterization of murine and human N-acetylglucosamine kinase. Eur J Biochem. 2000 Jun;267(11):3301-8
(Latest) J:188842 Bergfeld AK, et al., Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem. 2012 Aug 17;287(34):28865-81
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory