Nagk
Gene Detail

Symbol Name ID

Nagk N-acetylglucosamine kinase MGI:1860418

Synonyms

GlcNAc kinase

Feature Type

protein coding gene

Genetic Map

Chromosome 6

35.96 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr6:83794982-83803420 bp, + strand From VEGA annotation of GRCm38   8439 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Nagk ± 2 cM)

Gene Tree: Nagk

Human ortholog

NAGK N-acetylglucosamine kinase NCBI Gene ID 55577
Human Synonyms: GNK, HSA242910
Human Chr2:71295408-71305998 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(8) : Targeted(6) Gene trapped(2)
 

A gene trap insertion into an intron of this gene results in no obvious phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	carbohydrate phosphorylation, N-acetylglucosamine metabolic process, ...
Component	cellular_component
Function	ATP binding, kinase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)    Images (4)
Theiler Stages: 10, 18, 22, 23, 25, 28

Assay Type	Results
RNA in situ	94
Northern blot	12

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(8) cDNA(7) Other(1)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000023757 (Evidence)
Ensembl Gene Model	ENSMUSG00000034744 (Evidence)
Entrez Gene	56174 (Evidence)
DFCI	TC1580187, TC1611040, TC1616381, TC1681289
NIA Mouse Gene Index	U007088
EC	2.7.1.59
Consensus CDS Project	CCDS20286.1
International Mouse Knockout Project Status	Nagk

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023757	VEGA Gene Model | MGI Sequence Detail	8439	C57BL/6J
transcript	OTTMUST00000058044	VEGA | MGI Sequence Detail	1323	Not Applicable
polypeptide	OTTMUSP00000028071	VEGA | MGI Sequence Detail	361	Not Applicable

All sequences(47) RefSeq(4) UniProt(4)

Polymorphisms

SNPs(52 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002731	ATPase, BadF/BadG/BcrA/BcrD type
Protein Ontology	PR:000010960	N-acetyl-D-glucosamine kinase

References

(Earliest) J:62543 Hinderlich S, et al., Molecular cloning and characterization of murine and human N-acetylglucosamine kinase. Eur J Biochem. 2000 Jun;267(11):3301-8
(Latest) J:188842 Bergfeld AK, et al., Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem. 2012 Aug 17;287(34):28865-81
All references(33)