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Nagk
Gene Detail
 Symbol
Name
ID
Nagk
N-acetylglucosamine kinase
MGI:1860418
Synonyms GlcNAc kinase
Feature Type protein coding gene
Genetic Map
Chromosome 6
35.96 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:83794982-83803420 bp, + strand
From VEGA annotation of GRCm38

  8439 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9720  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Nagk

Human
homologs
Human Homolog NAGK, N-acetylglucosamine kinase
NCBI Gene ID 55577
neXtProt AC  NX_Q9UJ70
Human Synonyms  GNK, HSA242910
Human Chr (Location)  2p13.3; chr2:71068277-71078868 (+)  GRCh38
Alleles
and
phenotypes
All alleles(9) : Targeted(7) Gene trapped(2)
 
A gene trap insertion into an intron of this gene results in no obvious phenotype.
 
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process carbohydrate phosphorylation, N-acetylglucosamine metabolic process, ...
Component extracellular vesicular exosome
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)    Images (4)
Theiler Stages: 10, 18, 22, 23, 25, 28
Assay TypeResults
RNA in situ 94
Northern blot 12
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(8) cDNA(7) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000023757 (Evidence)
Ensembl Gene ModelENSMUSG00000034744 (Evidence)
Entrez Gene56174 (Evidence)
DFCITC1580187, TC1611040, TC1616381, TC1681289
NIA Mouse Gene IndexU007088
EC2.7.1.59
Consensus CDS ProjectCCDS20286.1
International Mouse Knockout Project StatusNagk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023757 VEGA Gene Model | MGI Sequence Detail 8439 C57BL/6J ±  kb
transcript OTTMUST00000058044 VEGA | MGI Sequence Detail 1323 Not Applicable 
polypeptide OTTMUSP00000028071 VEGA | MGI Sequence Detail 361 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(18) UniProt(4)
Polymorphisms SNPs within 2kb(66 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002731 ATPase, BadF/BadG/BcrA/BcrD type
Protein Ontology PR:000010960 N-acetyl-D-glucosamine kinase
References (Earliest) J:62543 Hinderlich S, et al., Molecular cloning and characterization of murine and human N-acetylglucosamine kinase. Eur J Biochem. 2000 Jun;267(11):3301-8
(Latest) J:188842 Bergfeld AK, et al., Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem. 2012 Aug 17;287(34):28865-81
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory