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Cd160 Gene Detail
Summary
  • Symbol
    Cd160
  • Name
    CD160 antigen
  • Synonyms
    By55
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860383
    NCBI Gene: 54215
  • Gene Overview
    MyGene.info: CD160
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96798763-96829351 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    126 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860383
protein coding gene Chr3:96798763-96829351 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027633
protein coding gene Chr3:97701368-97733371 (-)
A/J MGP_AJ_G0027595
protein coding gene Chr3:94571956-94603848 (-)
AKR/J MGP_AKRJ_G0027562
protein coding gene Chr3:96815333-96845696 (-)
BALB/cJ MGP_BALBcJ_G0027605
protein coding gene Chr3:94385397-94417972 (-)
C3H/HeJ MGP_C3HHeJ_G0027337
protein coding gene Chr3:97104558-97137721 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028051
protein coding gene Chr3:101264197-101297438 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025392
protein coding gene Chr3:90848767-90880104 (-)
CAST/EiJ MGP_CASTEiJ_G0026792
protein coding gene Chr3:96371227-96404338 (-)
CBA/J MGP_CBAJ_G0027312
protein coding gene Chr3:104978155-105011424 (-)
DBA/2J MGP_DBA2J_G0027455
protein coding gene Chr3:93899174-93929643 (-)
FVB/NJ MGP_FVBNJ_G0027424
protein coding gene Chr3:91910672-91944444 (-)
LP/J MGP_LPJ_G0027560
protein coding gene Chr3:98980504-99012462 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027450
protein coding gene Chr3:111051969-111085251 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028105
protein coding gene Chr3:96420900-96453594 (-)
PWK/PhJ MGP_PWKPhJ_G0026517
protein coding gene Chr3:93736876-93768864 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026339
protein coding gene Chr3:94723447-94755700 (-)
WSB/EiJ MGP_WSBEiJ_G0026870
protein coding gene Chr3:96872289-96908363 (-)



Homology
more
  • Human Ortholog
    CD160, CD160 molecule
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CD160, CD160 molecule
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BY55, NK1, NK28
  • Links
    NCBI Gene ID: 11126
    neXtProt AC: NX_O95971
    UniProt: O95971

  • Chr Location
    1q21.1; chr1:145719312-145739288 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Cd160
  • Incidental Mutations
  • Find Mice (IMSR)
Mice homozygous for a knock-out allele show decreased interferon-gamma secretion by NK cells and increased tumor growth/size following inoculation with NK-dependent B16 tumor cells.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54215 NCBI Gene Model | MGI Sequence Detail 30589 C57BL/6J ±  kb
transcript NM_001163496 RefSeq | MGI Sequence Detail 2590 C57BL/6  
polypeptide O88875 UniProt | EBI | MGI Sequence Detail 185 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 11
    Genomic 1
    cDNA 10

    Microarray probesets 7
Other
Accession IDs
less
MGI:2139919
References
more
  • Summaries
    All 35
    Diseases 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:266163 Seo GY, et al., LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection. Cell Host Microbe. 2018 Aug 8;24(2):249-260.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory