About   Help   FAQ
Ramp3 Gene Detail
Summary
  • Symbol
    Ramp3
  • Name
    receptor (calcitonin) activity modifying protein 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860292
    NCBI Gene: 56089
  • Gene Overview
    MyGene.info: RAMP3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:6658533-6677478 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 4.61 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860292
protein coding gene Chr11:6658521-6677478 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018030
protein coding gene Chr11:3809960-3828753 (+)
A/J MGP_AJ_G0018003
protein coding gene Chr11:3637744-3656534 (+)
AKR/J MGP_AKRJ_G0017967
protein coding gene Chr11:3819773-3838458 (+)
BALB/cJ MGP_BALBcJ_G0017971
protein coding gene Chr11:3646770-3665586 (+)
C3H/HeJ MGP_C3HHeJ_G0017784
protein coding gene Chr11:3703053-3725500 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018423
protein coding gene Chr11:3899846-3918688 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016081
protein coding gene Chr11:3524720-3544257 (+)
CAST/EiJ MGP_CASTEiJ_G0017346
protein coding gene Chr11:3695102-3716585 (+)
CBA/J MGP_CBAJ_G0017759
protein coding gene Chr11:4343748-4365024 (+)
DBA/2J MGP_DBA2J_G0017869
protein coding gene Chr11:3546813-3565934 (+)
FVB/NJ MGP_FVBNJ_G0017861
protein coding gene Chr11:3576412-3601456 (+)
LP/J MGP_LPJ_G0017940
protein coding gene Chr11:3870734-3889310 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017887
protein coding gene Chr11:3884639-3903514 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018463
protein coding gene Chr11:3845956-3866903 (+)
PWK/PhJ MGP_PWKPhJ_G0017126
protein coding gene Chr11:3587609-3606462 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016923
protein coding gene Chr11:3793820-3812235 (+)
WSB/EiJ MGP_WSBEiJ_G0017400
protein coding gene Chr11:3677640-3696333 (+)



Homology
more
  • Human Ortholog
    RAMP3, receptor activity modifying protein 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RAMP3, receptor activity modifying protein 3
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 10268
    neXtProt AC: NX_O60896
    UniProt: O60896

  • Chr Location
    7p13; chr7:45157768-45184250 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit decreased body weight at 6 months of age.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56089 NCBI Gene Model | MGI Sequence Detail 18946 C57BL/6J ±  kb
    transcript NM_019511 RefSeq | MGI Sequence Detail 1221 C57BL/6  
    polypeptide Q9WUP1 UniProt | EBI | MGI Sequence Detail 147 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2144304
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 6
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:61899 Ono Y, et al., Decreased gene expression of adrenomedullin receptor in mouse lungs during sepsis. Biochem Biophys Res Commun. 2000 Apr 29;271(1):197-202
    • Latest
      J:262098 Lutz TA, et al., Amylin Selectively Signals Onto POMC Neurons in the Arcuate Nucleus of the Hypothalamus. Diabetes. 2018 May;67(5):805-817

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    12/04/2018
    MGI 6.13
    The Jackson Laboratory