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Ramp3 Gene Detail
Summary
  • Symbol
    Ramp3
  • Name
    receptor (calcitonin) activity modifying protein 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860292
    NCBI Gene: 56089
  • Gene Overview
    MyGene.info: RAMP3
Location & Maps
more
  • Sequence Map
    Chr11:6658521-6677475 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18955 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 4.61 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RAMP3, receptor activity modifying protein 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RAMP3, receptor activity modifying protein 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10268
    neXtProt AC: NX_O60896

  • Chr Location
    7p13; chr7:45157768-45184250 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit decreased body weight at 6 months of age.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005124 VEGA Gene Model | MGI Sequence Detail 18955 C57BL/6J ±  kb
transcript OTTMUST00000011472 VEGA | MGI Sequence Detail 1233 Not Applicable  
polypeptide OTTMUSP00000005341 VEGA | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    84 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 17
    cDNA 17

    Microarray probesets 3
Other
Accession IDs
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MGI:2144304
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:61899 Ono Y, et al., Decreased gene expression of adrenomedullin receptor in mouse lungs during sepsis. Biochem Biophys Res Commun. 2000 Apr 29;271(1):197-202
  • Latest
    J:225780 Yamauchi A, et al., Functional differentiation of RAMP2 and RAMP3 in their regulation of the vascular system. J Mol Cell Cardiol. 2014 Dec;77:73-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory