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Ubqln2
Gene Detail
 Symbol
Name
ID
Ubqln2
ubiquilin 2
MGI:1860283
Synonyms Chap1, Dsk2, HRIHFB2157, Plic-2
Feature Type protein coding gene
Genetic Map
Chromosome X
68.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:153498227-153501570 bp, + strand
From VEGA annotation of GRCm38

  3344 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:81830  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Ubqln2

Human
homologs
Human Homolog UBQLN2, ubiquilin 2
NCBI Gene ID 29978
neXtProt AC  NX_Q9UHD9
Human Synonyms  ALS15, CHAP1, DSK2, N4BP4, PLIC2
Human Chr (Location)  Xp11.21; chrX:56563593-56567010 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human UBQLN2
Alleles
and
phenotypes
All alleles(1) : Gene trapped(1)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Component cytoplasm, membrane, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)   
Theiler Stages: 21
Assay TypeResults
RNA in situ 1
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(5) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000019381 (Evidence)
Ensembl Gene ModelENSMUSG00000050148 (Evidence)
Entrez Gene54609 (Evidence)
DFCITC1574265
DoTSDT.50315965, DT.91342023
NIA Mouse Gene IndexU020340
Consensus CDS ProjectCCDS30482.1
International Mouse Knockout Project StatusUbqln2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019381 VEGA Gene Model | MGI Sequence Detail 3344 C57BL/6J ±  kb
transcript OTTMUST00000046253 VEGA | MGI Sequence Detail 3344 Not Applicable 
polypeptide OTTMUSP00000020893 VEGA | MGI Sequence Detail 638 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(11 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR006636 Heat shock chaperonin-binding
InterPro IPR009060 UBA-like
InterPro IPR015496 Ubiquilin
InterPro IPR000626 Ubiquitin
InterPro IPR000449 Ubiquitin-associated/translation elongation factor EF1B, N-terminal
InterPro IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote
Protein Ontology PR:000017008 ubiquilin-2
References (Earliest) J:62988 Wu AL, et al., Ubiquitin-related proteins regulate interaction of vimentin intermediate filaments with the plasma membrane. Mol Cell. 1999 Oct;4(4):619-25
(Latest) J:206933 Farg MA, et al., C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Hum Mol Genet. 2014 Feb 27;
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory