Sema3d
Gene Detail

Symbol Name ID

Sema3d sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D MGI:1860118

Synonyms

4631426B19Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 5

3.97 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr5:12383166-12588943 bp, + strand From NCBI annotation of GRCm38   205778 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:23664  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: semaphorin
Gene Tree: Sema3d

Human homologs

Human Homolog		SEMA3D, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
NCBI Gene ID		223117
neXtProt AC		NX_O95025
Human Synonyms		coll-2, Sema-Z2
Human Chr (Location)		7q21.11; chr7:84624869-84751247 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	cell differentiation, multicellular organismal development, ...
Component	extracellular region, membrane
Function	receptor activity

External Resources: FuncBase

Expression

Literature Summary: (13 records)
Data Summary: Results (166)    Tissues (30)    Images (23)
Theiler Stages: 20, 21, 22, 23

Assay Type	Results
RNA in situ	166

cDNA source data(34)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(35) cDNA(34) Primer pair(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000040254 (Evidence)
Entrez Gene	108151 (Evidence)
UniGene	89313
DFCI	TC1581670, TC1593838, TC1599127, TC1641388
DoTS	DT.110648143, DT.40153683, DT.40180653, DT.91290089, DT.91327830, DT.94189489, DT.97394214
NIA Mouse Gene Index	U005291
Consensus CDS Project	CCDS39013.1
International Mouse Knockout Project Status	Sema3d

Sequences

Length	Strain/Species
genomic	108151	NCBI Gene Model | MGI Sequence Detail	205778	C57BL/6J
transcript	NM_028882	RefSeq | MGI Sequence Detail	6521	C57BL/6
polypeptide	Q8BH34	UniProt | EBI | MGI Sequence Detail	777	Not Applicable

All sequences(37) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(1325 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003599	Immunoglobulin subtype
InterPro	IPR013106	Immunoglobulin V-set
InterPro	IPR016201	Plexin-like fold
InterPro	IPR003659	Plexin/semaphorin/integrin
InterPro	IPR001627	Semaphorin/CD100 antigen
InterPro	IPR015943	WD40/YVTN repeat-like-containing domain
Protein Ontology	PR:000014618	semaphorin-3D

Graphical View of Protein Domain Structure

References

(Earliest) J:62530 Tarantino LM, et al., A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5. Genomics. 2000 May 15;66(1):55-64
(Latest) J:192712 Meadows SM, et al., Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels. Circ Res. 2012 Jan 6;110(1):34-46
All references(42)

Other accession IDs

MGI:1921595