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Stard10 Gene Detail
Summary
  • Symbol
    Stard10
  • Name
    START domain containing 10
  • Synonyms
    CGI-52, NY-C0-28, PCTP2, PC-TP2, Pctpl, Sdccag28, TISP-81
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860093
    NCBI Gene: 56018
  • Gene Overview
    MyGene.info: STARD10
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr7:101317086-101346626 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      29541 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.55 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    STARD10, StAR related lipid transfer domain containing 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STARD10, StAR related lipid transfer domain containing 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-52, NY-CO-28, PCTP2, SDCCAG28
  • Links
    NCBI Gene ID: 10809
    neXtProt AC: NX_Q9Y365
    UniProt: Q9Y365

  • Chr Location
    11q13.4; chr11:72754729-72793705 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit altered bile acid homeostasis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000037676 VEGA Gene Model | MGI Sequence Detail 29541 C57BL/6J ±  kb
    transcript OTTMUST00000097291 VEGA | MGI Sequence Detail 1723 Not Applicable  
    polypeptide OTTMUSP00000054553 VEGA | MGI Sequence Detail 364 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      242 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      13 Sequences
    • InterPro Domains
      IPR002913 START domain
      IPR023393 START-like domain superfamily
    Molecular
    Reagents
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    • All nucleic 151
      Genomic 1
      cDNA 150

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:3035478
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 17
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:240691 Carrat GR, et al., Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice. Am J Hum Genet. 2017 Feb 02;100(2):238-256

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory