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Hebp2 Gene Detail
Summary
  • Symbol
    Hebp2
  • Name
    heme binding protein 2
  • Synonyms
    SOUL
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860084
    NCBI Gene: 56016
  • Gene Overview
    MyGene.info: HEBP2
Location & Maps
more
  • Sequence Map
    Chr10:18540123-18546076 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5954 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 7.76 cM, cytoband A2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    HEBP2, heme binding protein 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HEBP2, heme binding protein 2
    Orthology source: HomoloGene
  • Synonyms
    C6orf34, C6ORF34B, PP23, SOUL
  • Links
    NCBI Gene ID: 23593
    neXtProt AC: NX_Q9Y5Z4

  • Chr Location
    6q24; chr6:138404199-138421545 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Hebp2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56016 NCBI Gene Model | MGI Sequence Detail 5954 C57BL/6J ±  kb
transcript NM_019487 RefSeq | MGI Sequence Detail 1910 C57BL/6  
polypeptide Q9WU63 UniProt | EBI | MGI Sequence Detail 205 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    149 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008500 heme-binding protein 2
  • InterPro Domains
    IPR011256 Regulatory factor, effector binding domain
    IPR006917 SOUL haem-binding protein
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 6
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:59128 Zylka MJ, et al., Discovery of a putative heme-binding protein family (SOUL/HBP) by two-tissue suppression subtractive hybridization and database searches. Brain Res Mol Brain Res. 1999 Dec 10;74(1-2):175-81
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory