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Prdx5 Gene Detail
Summary
  • Symbol
    Prdx5
  • Name
    peroxiredoxin 5
  • Synonyms
    AOEB166, AOPP, peroxiredoxin V, PMP20, Prdx6, PrxV, PrxV
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859821
    NCBI Gene: 54683
  • Gene Overview
    MyGene.info: PRDX5
Location & Maps
more
  • Genetic Map
    Chromosome 19, 5.08 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
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  • Human Ortholog
    PRDX5, peroxiredoxin 5
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PRDX5, peroxiredoxin 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, prx-V, PRXV, SBBI10
  • Links
    NCBI Gene ID: 25824
    neXtProt AC: NX_P30044

  • Chr Location
    11q13; chr11:64318088-64321823 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    3
  • Targeted
    3
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021180 VEGA Gene Model | MGI Sequence Detail 3410 C57BL/6J ±  kb
transcript OTTMUST00000050173 VEGA | MGI Sequence Detail 755 Not Applicable  
polypeptide OTTMUSP00000057784 VEGA | MGI Sequence Detail 213 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    52 from dbSNP Build 142
  • PCR
Protein
Information
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Molecular
Reagents
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  • All nucleic 249
    cDNA 248
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
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MGI:1349456
References
more
  • Summaries
    All 45
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:58008 Yamashita H, et al., Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro. J Biol Chem. 1999 Oct 15;274(42):29897-904
  • Latest
    J:227089 Pirson M, et al., Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory