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Rpp30 Gene Detail
Summary
  • Symbol
    Rpp30
  • Name
    ribonuclease P/MRP 30 subunit
  • Synonyms
    Rnasep2, TSG15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859683
    NCBI Gene: 54364
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:36061118-36082173 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 30.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    799 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859683
 protein coding gene Chr19:36061116-36082177 (+)
129S1/SvImJ ENSMUSG00200029996
 protein coding gene Chr19:32830514-32851716 (+)
A/J ENSMUSG00195011109
 protein coding gene Chr19:32951455-32972654 (+)
AKR/J ENSMUSG00220017206
 protein coding gene Chr19:32835211-32856305 (+)
BALB/cJ ENSMUSG00180027105
 protein coding gene Chr19:33280262-33301366 (+)
C3H/HeJ ENSMUSG00175038894
 protein coding gene Chr19:32707528-32728654 (+)
C57BL/6NJ ENSMUSG00215021391
 protein coding gene Chr19:32725420-32746561 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022902
 protein coding gene Chr19:32643261-32664703 (+)
CAST/EiJ ENSTCUG00005015526
 protein coding gene Chr19:32360461-32381557 (+)
CBA/J ENSMUSG00210034021
 protein coding gene Chr19:32786776-32807998 (+)
DBA/2J ENSMUSG00185029020
 protein coding gene Chr19:33306944-33328174 (+)
FVB/NJ ENSMUSG00205006690
 protein coding gene Chr19:32551737-32572948 (+)
JF1/MsJ ENSUMUG00000042401
 protein coding gene Chr19:33438107-33459325 (+)
LP/J ENSMUSG00230029969
 protein coding gene Chr19:34117966-34139066 (+)
NOD/ShiLtJ ENSMUSG00190009417
 protein coding gene Chr19:32690884-32711982 (+)
NZO/HlLtJ ENSMUSG00225029134
 protein coding gene Chr19:37674580-37695791 (+)
PWK/PhJ ENSLUMG00010001157
 protein coding gene Chr19:32817857-32839079 (+)
SPRET/EiJ ENSMSPG00010018119
 protein coding gene Chr19:32535172-32556035 (+)
WSB/EiJ ENSIUOG00005035627
 protein coding gene Chr19:32194669-32215877 (+)



Homology
more
  • Human Ortholog
    RPP30, ribonuclease P/MRP subunit p30
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPP30, ribonuclease P/MRP subunit p30
  • Synonyms
    TSG15
  • Links
    NCBI Gene ID: 10556
    UniProt: P78346

  • Chr Location
    10q23.31; chr10:90871487-90908556 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    13
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54364 NCBI Gene Model | MGI Sequence Detail 21056 C57BL/6J ±  kb
transcript NM_019428 RefSeq | MGI Sequence Detail 1154 C57BL/6  
polypeptide O88796 UniProt | EBI | MGI Sequence Detail 268 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:2316 Hoog C, Isolation of a large number of novel mammalian genes by a differential cDNA library screening strategy. Nucleic Acids Res. 1991 Nov 25;19(22):6123-7
  • Latest
    J:380397 Goldbraikh D, et al., USP1 deubiquitinates Akt to inhibit PI3K-Akt-FoxO signaling in muscle during prolonged starvation. EMBO Rep. 2020 Apr 3;21(4):e48791
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory