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Slc23a2
Gene Detail
Symbol

Name
ID
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
MGI:1859682
Synonyms
mKIAA0238, Slc23a1, SVCT2, YSPL3
Feature Type
protein coding gene
Genetic Map
Chromosome 2
64.15 cM, cytoband G2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:132052496-132145108 bp, - strand
From VEGA annotation of GRCm38

  92613 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68440  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: xanthine/uracil permease
Gene Tree: Slc23a2

Human
homologs
Human Homolog SLC23A2, solute carrier family 23 (ascorbic acid transporter), member 2
NCBI Gene ID 9962
neXtProt AC  NX_Q9UGH3
Human Synonyms  NBTL1, SLC23A1, SVCT2, YSPL2
Human Chr (Location)  20p13; chr20:4852356-5010293 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(52) : Gene trapped(47) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene die within minutes of birth from respiratory distress.
 
Interactions
Slc23a2 interacts with 427 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (68)    Tissues (33)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 68
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000015783 (Evidence)
Ensembl Gene ModelENSMUSG00000027340 (Evidence)
Entrez Gene54338 (Evidence)
DFCITC1613376, TC1587855, TC1653346
DoTSDT.487007, DT.103566947
NIA Mouse Gene IndexU023388
Consensus CDS ProjectCCDS16769.1
International Mouse Knockout Project StatusSlc23a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015783 VEGA Gene Model | MGI Sequence Detail 92613 C57BL/6J ±  kb
transcript OTTMUST00000037505 VEGA | MGI Sequence Detail 6364 Not Applicable 
polypeptide OTTMUSP00000016807 VEGA | MGI Sequence Detail 648 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(458 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006042 Xanthine/uracil permease
InterPro IPR006043 Xanthine/uracil/vitamin C permease
Protein Ontology PR:000014997 solute carrier family 23 member 2
References
(Earliest) J:50857 Faaland CA, et al., Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters. Biochim Biophys Acta. 1998 Nov 8;1442(2-3):353-60
(Latest) J:206636 Nualart F, et al., Dynamic expression of the sodium-vitamin C co-transporters, SVCT1 and SVCT2, during perinatal kidney development. Histochem Cell Biol. 2013 Feb;139(2):233-47
All references(59)
Other
accession IDs
MGI:2139069

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory