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Ctnnal1 Gene Detail
Summary
  • Symbol
    Ctnnal1
  • Name
    catenin (cadherin associated protein), alpha-like 1
  • Synonyms
    ACRP, Catnal1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859649
    NCBI Gene: 54366
  • Gene Overview
    MyGene.info: CTNNAL1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:56810935-56865188 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 31.66 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    283 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859649
protein coding gene Chr4:56810935-56865379 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028312
protein coding gene Chr4:55573321-55632829 (-)
A/J MGP_AJ_G0028273
protein coding gene Chr4:53451595-53507986 (-)
AKR/J MGP_AKRJ_G0028222
protein coding gene Chr4:54924749-54984627 (-)
BALB/cJ MGP_BALBcJ_G0028292
protein coding gene Chr4:53607113-53661452 (-)
C3H/HeJ MGP_C3HHeJ_G0028013
protein coding gene Chr4:55433631-55488702 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028733
protein coding gene Chr4:57557789-57615303 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026039
protein coding gene Chr4:50257936-50308846 (-)
CAST/EiJ MGP_CASTEiJ_G0027451
protein coding gene Chr4:55138820-55198724 (-)
CBA/J MGP_CBAJ_G0027978
protein coding gene Chr4:59540075-59596947 (-)
DBA/2J MGP_DBA2J_G0028128
protein coding gene Chr4:53358661-53412904 (-)
FVB/NJ MGP_FVBNJ_G0028095
protein coding gene Chr4:52568640-52624093 (-)
LP/J MGP_LPJ_G0028227
protein coding gene Chr4:55674576-55733044 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028119
protein coding gene Chr4:62703847-62767837 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028769
protein coding gene Chr4:55103250-55159834 (-)
PWK/PhJ MGP_PWKPhJ_G0027176
protein coding gene Chr4:53339961-53396565 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027004
protein coding gene Chr4:54384723-54441971 (-)
WSB/EiJ MGP_WSBEiJ_G0027529
protein coding gene Chr4:55058737-55115689 (-)



Homology
more
  • Human Ortholog
    CTNNAL1, catenin alpha like 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CTNNAL1, catenin alpha like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ACRP, alpha-CATU, CLLP
  • Links
    NCBI Gene ID: 8727
    neXtProt AC: NX_Q9UBT7
    UniProt: Q9UBT7

  • Chr Location
    9q31.3; chr9:108942569-109013594 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Mice homozygous for a targeted disruption of this gene are viable and fertile and exhibit no overt phenotypes or defects in hematopoiesis and hematopoietic stem cell function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038816 Ensembl Gene Model | MGI Sequence Detail 54254 C57BL/6J ±  kb
transcript ENSMUST00000045142 Ensembl | MGI Sequence Detail 3664 Not Applicable  
polypeptide ENSMUSP00000036487 Ensembl | MGI Sequence Detail 731 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    cDNA 63

    Microarray probesets 6
Other
Accession IDs
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MGI:2140345, MGI:2140586, MGI:2140700
References
more
  • Summaries
    All 39
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:229960 Acar M, et al., Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal. Nature. 2015 Oct 1;526(7571):126-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory