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Ftsj1
Gene Detail
Symbol

Name
ID
Ftsj1
FtsJ homolog 1 (E. coli)
MGI:1859648
Synonyms
Sfc12
Feature Type
protein coding gene
Genetic Map
Chromosome X
3.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
ChrX:8238668-8252406 bp, - strand
From VEGA annotation of GRCm38

  13739 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5372  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: 23S ribosomal RNA methyltransferase
Gene Tree: Ftsj1

Human
homologs
Human Homolog FTSJ1, FtsJ RNA methyltransferase homolog 1 (E. coli)
NCBI Gene ID 24140
neXtProt AC  NX_Q9UET6
Human Synonyms  CDLIV, MRX44, MRX9, SPB1, TRMT7
Human Chr (Location)  Xp11.23; chrX:48476021-48486364 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human FTSJ1
Mutations,
alleles, and
phenotypes
All mutations/alleles(40) : Gene trapped(36) Targeted(4)
Incidental mutations (data from APF )
 
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
 
Phenotype Images(6)
Interactions
Ftsj1 interacts with 243 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(76)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(83) Genomic(6) cDNA(77)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000018132 (Evidence)
Ensembl Gene ModelENSMUSG00000031171 (Evidence)
Entrez Gene54632 (Evidence)
UniGene327529
DFCITC1589227, TC1576218
DoTSDT.101234226, DT.101407689, DT.101407690, DT.99859354, DT.94131006
NIA Mouse Gene IndexU039245
EC2.1.1.205
Consensus CDS ProjectCCDS29994.1, CCDS72340.1
International Mouse Knockout Project StatusFtsj1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018132 VEGA Gene Model | MGI Sequence Detail 13739 C57BL/6J ±  kb
transcript OTTMUST00000043792 VEGA | MGI Sequence Detail 3425 Not Applicable 
polypeptide OTTMUSP00000019665 VEGA | MGI Sequence Detail 324 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(4) UniProt(10)
Polymorphisms
SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015507 Ribosomal RNA large subunit methyltransferase E
InterPro IPR002877 Ribosomal RNA methyltransferase FtsJ domain
Protein Ontology PR:000029728 ribosomal RNA methyltransferase 1
References
(Earliest) J:62168 Means GD, et al., A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Genomics. 2000 May 1;65(3):213-23
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:2147938

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory