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Ftsj1
Gene Detail
Symbol

Name
ID
Ftsj1
FtsJ homolog 1 (E. coli)
MGI:1859648
Synonyms
Sfc12
Feature Type
protein coding gene
Genetic Map
Chromosome X
3.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
ChrX:8238668-8252406 bp, - strand
From VEGA annotation of GRCm38

  13739 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5372  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: FTSJ1
Protein SuperFamily: 23S ribosomal RNA methyltransferase
Gene Tree: Ftsj1

Human
homologs
FTSJ1, FtsJ RNA methyltransferase homolog 1 (E. coli)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 24140
neXtProt AC: NX_Q9UET6

Human Synonyms: CDLIV, JM23, MRX44, MRX9, SPB1, TRMT7

Human Chr (Location): Xp11.23; chrX:48476021-48486364 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human FTSJ1

Mutations,
alleles, and
phenotypes
All mutations/alleles(40) : Gene trapped(36) Targeted(4)
Incidental mutations (data from APF )
 
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
 
Phenotype Images(6)
Interactions
Ftsj1 interacts with 243 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(76)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ftsj1    NEW 
Molecular
reagents
All nucleic(83) Genomic(6) cDNA(77)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000018132 (Evidence)
Ensembl Gene Model ENSMUSG00000031171 (Evidence)
Entrez Gene 54632 (Evidence)
UniGene 327529
DFCI TC1589227, TC1576218
DoTS DT.101407690, DT.94131006, DT.101407689, DT.101234226, DT.99859354
NIA Mouse Gene Index U039245
EC 2.1.1.205
Consensus CDS Project CCDS29994.1, CCDS72340.1
International Mouse Phenotyping Consortium Status Ftsj1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018132 VEGA Gene Model | MGI Sequence Detail 13739 C57BL/6J ±  kb
transcript OTTMUST00000043792 VEGA | MGI Sequence Detail 3425 Not Applicable 
polypeptide OTTMUSP00000019665 VEGA | MGI Sequence Detail 324 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015507 Ribosomal RNA large subunit methyltransferase E
InterPro IPR002877 Ribosomal RNA methyltransferase FtsJ domain
Protein Ontology PR:000029728 ribosomal RNA methyltransferase 1
References
(Earliest) J:62168 Means GD, et al., A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Genomics. 2000 May 1;65(3):213-23
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGI:2147938

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory