Ppp1r3f Gene Detail

Summary

• Symbol
  Ppp1r3f
• Name
  protein phosphatase 1, regulatory (inhibitor) subunit 3F
• Synonyms
  DXImx48e, RF3, Sfc15

• Feature Type
  protein coding gene
• IDs
  MGI:1859617
  NCBI Gene: 54646

Location & Maps

• Sequence Map
  ChrX:7557296-7574283 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    16988 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome X, 3.40 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  PPP1R3F, protein phosphatase 1 regulatory subunit 3F

• Vertebrate Orthologs
  5

• Human Ortholog
  PPP1R3F, protein phosphatase 1 regulatory subunit 3F
  Orthology source: HomoloGene, HGNC
• Synonyms
  HB2E, LL0XNC01-7P3.1, R3F
• Links
  HGNC:14944

  NCBI Gene ID: 89801

  neXtProt AC: NX_Q6ZSY5

  UniProt: Q6ZSY5

  
  
• Chr Location
  Xp11.23; chrX:49269822-49301465 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 16330
  1 human;1 mouse;1 cattle;1 dog;1 macaque, rhesus
  
• HCOP
  human homology predictions: PPP1R3F
• Gene Tree
  Ppp1r3f
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  3
• Targeted
  3
• Incidental Mutations
  CvDC
• Find Mice (IMSR)
  5 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  6
• GO References
  2

• External Resources
  FuncBase

Expression

• Assay Results
  20
• Tissues
  2
• cDNA Data
  10
• Literature Summary
  1

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Ppp1r3f interacts with 305 markers (Mir7-1, Mir7-2, Mir9-1, ...) View All

Sequences &
Gene Models

• All Sequences
  33
• RefSeq
  4
• UniProt
  3
• CCDS
  CCDS29964.2, CCDS72328.1
• UniGene
  148163

• VEGA
  OTTMUSG00000016549 (Evidence)
• Ensembl
  ENSMUSG00000039556 (Evidence)
• NCBI Gene
  54646

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000016549	VEGA Gene Model | MGI Sequence Detail	16988	C57BL/6J
transcript	OTTMUST00000039999	VEGA | MGI Sequence Detail	4760	Not Applicable
polypeptide	OTTMUSP00000017841	VEGA | MGI Sequence Detail	800	Not Applicable

Polymorphisms

• SNPs within 2kb
  31 from dbSNP Build 142

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000013129 protein phosphatase 1 regulatory subunit 3F
  (term hierarchy)
• InterPro Domains
  IPR005036 CBM21 (carbohydrate binding type-21) domain
  IPR013783 Immunoglobulin-like fold

Molecular
Reagents

• All nucleic 15

  Genomic 5

  cDNA 10

  
  

  Microarray probesets 3

References

• Summaries
  All 22

  Developmental Gene Expression 1

  Gene Ontology 2

  Phenotypes 2
• Earliest
  J:62168 Means GD, et al., A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Genomics. 2000 May 1;65(3):213-23
• Latest
  J:175462 Kelsall IR, et al., R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signals. J Neurochem. 2011 Aug;118(4):596-610