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Sfmbt1 Gene Detail
Summary
  • Symbol
    Sfmbt1
  • Name
    Scm-like with four mbt domains 1
  • Synonyms
    4930442N21Rik, 9330180L21Rik, Smr
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859609
    NCBI Gene: 54650
  • Gene Overview
    MyGene.info: SFMBT1
Location & Maps
more
  • Sequence Map
    Chr14:30714849-30822713 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      107865 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 18.99 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SFMBT1, Scm-like with four mbt domains 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SFMBT1, Scm-like with four mbt domains 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hSFMBT, RU1, SFMBT
  • Links
    NCBI Gene ID: 51460
    neXtProt AC: NX_Q9UHJ3

  • Chr Location
    3p21.1; chr3:52899982-53046655 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025116 VEGA Gene Model | MGI Sequence Detail 107865 C57BL/6J ±  kb
transcript OTTMUST00000061783 VEGA | MGI Sequence Detail 2936 Not Applicable  
polypeptide OTTMUSP00000030379 VEGA | MGI Sequence Detail 863 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    526 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 72
    Genomic 2
    cDNA 69
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1924518, MGI:1925411, MGI:2145571
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:62166 Usui H, et al., Cloning of a novel murine gene Sfmbt, Scm-related gene containing four mbt domains, structurally belonging to the Polycomb group of genes. Gene. 2000 May 2;248(1-2):127-35
  • Latest
    J:195484 Zhang J, et al., SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors. Genes Dev. 2013 Apr 1;27(7):749-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory