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Sfmbt1 Gene Detail
Summary
  • Symbol
    Sfmbt1
  • Name
    Scm-like with four mbt domains 1
  • Synonyms
    4930442N21Rik, 9330180L21Rik, Smr
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859609
    NCBI Gene: 54650
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:30436806-30544678 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 18.99 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    526 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859609
protein coding gene Chr14:30436806-30544678 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021107
protein coding gene Chr14:23851422-23960073 (+)
A/J MGP_AJ_G0021055
protein coding gene Chr14:22967825-23075287 (+)
AKR/J MGP_AKRJ_G0021032
protein coding gene Chr14:24078773-24184667 (+)
BALB/cJ MGP_BALBcJ_G0021059
protein coding gene Chr14:23068162-23173595 (+)
C3H/HeJ MGP_C3HHeJ_G0020842
protein coding gene Chr14:23937794-24046052 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021491
protein coding gene Chr14:24808883-24920308 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019054
protein coding gene Chr14:23025354-23134481 (+)
CAST/EiJ MGP_CASTEiJ_G0020367
protein coding gene Chr14:23688711-23793801 (+)
CBA/J MGP_CBAJ_G0020809
protein coding gene Chr14:25760126-25875762 (+)
DBA/2J MGP_DBA2J_G0020931
protein coding gene Chr14:22999749-23099253 (+)
FVB/NJ MGP_FVBNJ_G0020915
protein coding gene Chr14:22954743-23057159 (+)
LP/J MGP_LPJ_G0021000
protein coding gene Chr14:24177517-24291077 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020941
protein coding gene Chr14:25041911-25155501 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021524
protein coding gene Chr14:23823289-23936014 (+)
PWK/PhJ MGP_PWKPhJ_G0020115
protein coding gene Chr14:22435449-22547448 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019939
protein coding gene Chr14:23417456-23516938 (+)
WSB/EiJ MGP_WSBEiJ_G0020422
protein coding gene Chr14:23888702-23996375 (+)



Homology
more
  • Human Ortholog
    SFMBT1, Scm like with four mbt domains 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SFMBT1, Scm like with four mbt domains 1
  • Synonyms
    hSFMBT, RU1, SFMBT
  • Links
    NCBI Gene ID: 51460
    neXtProt AC: NX_Q9UHJ3
    UniProt: Q9UHJ3

  • Chr Location
    3p21.1; chr3:52903572-53046750 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 54650 NCBI Gene Model | MGI Sequence Detail 107873 C57BL/6J ±  kb
transcript NM_001166532 RefSeq | MGI Sequence Detail 7837 ZRU/MplStud  
polypeptide Q9JMD1 UniProt | EBI | MGI Sequence Detail 863 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 74
    Genomic 2
    cDNA 71
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1924518, MGI:1925411, MGI:2145571
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:62166 Usui H, et al., Cloning of a novel murine gene Sfmbt, Scm-related gene containing four mbt domains, structurally belonging to the Polycomb group of genes. Gene. 2000 May 2;248(1-2):127-35
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory