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Slc22a7
Gene Detail
Symbol

Name
ID
Slc22a7
solute carrier family 22 (organic anion transporter), member 7
MGI:1859559
Synonyms
NLT, OAT2
Feature Type
protein coding gene
Genetic Map
Chromosome 17
22.90 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:46432185-46438477 bp, - strand
From NCBI annotation of GRCm38

  6293 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21328  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Slc22a7

Human
homologs
Human Homolog SLC22A7, solute carrier family 22 (organic anion transporter), member 7
NCBI Gene ID 10864
neXtProt AC  NX_Q9Y694
Human Synonyms  NLT, OAT2
Human Chr (Location)  6p21.1; chr6:43298260-43305538 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc22a7 interacts with 46 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (17)    Tissues (17)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 15
RT-PCR 2
cDNA source data(48)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(51) Genomic(1) cDNA(48) Primer pair(2)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000067144 (Evidence)
Entrez Gene108114 (Evidence)
UniGene387538
DFCITC1580408
DoTSDT.101142225, DT.525581
Consensus CDS ProjectCCDS28829.1
International Mouse Knockout Project StatusSlc22a7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 108114 NCBI Gene Model | MGI Sequence Detail 6293 C57BL/6J ±  kb
transcript NM_144856 RefSeq | MGI Sequence Detail 2007 C57BL/6 
polypeptide Q91WU2 UniProt | EBI | MGI Sequence Detail 540 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(21 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005828 General substrate transporter
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
InterPro IPR004749 Organic cation transport protein
Protein Ontology PR:000014994 solute carrier family 22 member 7
Graphical View of Protein Domain Structure
References
(Earliest) J:61599 Pavlova A, et al., Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol. 2000 Apr;278(4):F635-43
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory