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Slc22a7
Gene Detail
Symbol

Name
ID
Slc22a7
solute carrier family 22 (organic anion transporter), member 7
MGI:1859559
Synonyms
NLT, OAT2
Feature Type
protein coding gene
Genetic Map
Chromosome 17
22.90 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:46432185-46438477 bp, - strand
From NCBI annotation of GRCm38

  6293 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21328  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: SLC22A7
Gene Tree: Slc22a7

Human
homologs
SLC22A7, solute carrier family 22 (organic anion transporter), member 7
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10864
neXtProt AC: NX_Q9Y694

Human Synonyms: NLT, OAT2

Human Chr (Location): 6p21.1; chr6:43295710-43305538 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Slc22a7 interacts with 46 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (17)    Tissues (17)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 15
RT-PCR 2
cDNA source data(48)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc22a7 ; ZFIN slc22a7a, slc22a7b.1    NEW 
Molecular
reagents
All nucleic(51) Genomic(1) cDNA(48) Primer pair(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000067144 (Evidence)
Entrez Gene 108114 (Evidence)
UniGene 387538
DFCI TC1580408
DoTS DT.525581, DT.101142225
Consensus CDS Project CCDS28829.1
International Mouse Phenotyping Consortium Status Slc22a7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 108114 NCBI Gene Model | MGI Sequence Detail 6293 C57BL/6J ±  kb
transcript NM_144856 RefSeq | MGI Sequence Detail 2007 C57BL/6 
polypeptide Q91WU2 UniProt | EBI | MGI Sequence Detail 540 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(21 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005828 General substrate transporter
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR004749 Organic cation transport protein
Protein Ontology PR:000014994 solute carrier family 22 member 7
Graphical View of Protein Domain Structure
References
(Earliest) J:61599 Pavlova A, et al., Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol. 2000 Apr;278(4):F635-43
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory