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Nup210 Gene Detail
Summary
  • Symbol
    Nup210
  • Name
    nucleoporin 210
  • Synonyms
    gp190, gp210, Pom210
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859555
    NCBI Gene: 54563
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:91013068-91116829 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 40.30 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    928 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859555
protein coding gene Chr6:91013067-91117010 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031042
protein coding gene Chr6:92586558-92695364 (-)
A/J MGP_AJ_G0031010
protein coding gene Chr6:89060139-89165180 (-)
AKR/J MGP_AKRJ_G0030942
protein coding gene Chr6:91530453-91640081 (-)
BALB/cJ MGP_BALBcJ_G0031022
protein coding gene Chr6:89001291-89105651 (-)
C3H/HeJ MGP_C3HHeJ_G0030686
protein coding gene Chr6:92799280-92910108 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031481
protein coding gene Chr6:95002589-95116167 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028649
protein coding gene Chr6:87037098-87142838 (-)
CAST/EiJ MGP_CASTEiJ_G0030129
protein coding gene Chr6:91646184-91755101 (-)
CBA/J MGP_CBAJ_G0030708
protein coding gene Chr6:98531910-98646459 (-)
DBA/2J MGP_DBA2J_G0030861
protein coding gene Chr6:88246416-88350527 (-)
FVB/NJ MGP_FVBNJ_G0030815
protein coding gene Chr6:87453982-87556806 (-)
LP/J MGP_LPJ_G0030941
protein coding gene Chr6:92544480-92654619 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030849
protein coding gene Chr6:102612294-102721146 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031508
protein coding gene Chr6:91373803-91484710 (-)
PWK/PhJ MGP_PWKPhJ_G0029845
protein coding gene Chr6:87171299-87296446 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029674
protein coding gene Chr6:90283150-90393641 (-)
WSB/EiJ MGP_WSBEiJ_G0030213
protein coding gene Chr6:91833278-91941832 (-)



Homology
more
  • Human Ortholog
    NUP210, nucleoporin 210
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUP210, nucleoporin 210
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GP210, POM210
  • Links
    NCBI Gene ID: 23225
    neXtProt AC: NX_Q8TEM1
    UniProt: Q8TEM1

  • Chr Location
    3p25.1; chr3:13316230-13420319 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41286
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NUP210
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 3 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit decreased naive T cells and increased activated T cells due to impaired peripheral T cell development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030091 Ensembl Gene Model | MGI Sequence Detail 103762 C57BL/6J ±  kb
transcript ENSMUST00000032179 Ensembl | MGI Sequence Detail 7037 Not Applicable  
polypeptide ENSMUSP00000032179 Ensembl | MGI Sequence Detail 1886 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 95
    cDNA 93
    Primer pair 1
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2141476
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:59628 Olsson M, et al., cDNA cloning and embryonic expression of mouse nuclear pore membrane glycoprotein 210 mRNA. Kidney Int. 1999 Sep;56(3):827-38
  • Latest
    J:266693 van Nieuwenhuijze A, et al., Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations. Front Immunol. 2018;9:2234

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory