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Lrrc6
Gene Detail
Symbol

Name
ID
Lrrc6
leucine rich repeat containing 6 (testis)
MGI:1859553
Synonyms
LRTP
Feature Type
protein coding gene
Genetic Map
Chromosome 15
29.22 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:66379858-66500910 bp, - strand
From VEGA annotation of GRCm38

  121053 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:34534  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LRRC6
Gene Tree: Lrrc6

Human
homologs
LRRC6, leucine rich repeat containing 6
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 23639
neXtProt AC: NX_Q86X45

Human Synonyms: CILD19, LRTP, TSLRP

Human Chr (Location): 8q24.22; chr8:132570416-132685097 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human LRRC6

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Radiation induced(1) Targeted(1)
Genomic Mutations involving Lrrc6 (1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(2)
Interactions
Lrrc6 interacts with 96 markers (Mir19a, Mir22, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cilium movement, epithelial cilium movement involved in determination of left/right asymmetry, ...
Component cell projection, cilium, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase lrrc6 ; ZFIN lrrc6    NEW 
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000037898 (Evidence)
Ensembl Gene Model ENSMUSG00000022375 (Evidence)
Entrez Gene 54562 (Evidence)
UniGene 244890
DFCI TC1584226
DoTS DT.40141158
NIA Mouse Gene Index U036242
Consensus CDS Project CCDS49620.1
International Mouse Phenotyping Consortium Status Lrrc6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037898 VEGA Gene Model | MGI Sequence Detail 121053 C57BL/6J ±  kb
transcript OTTMUST00000097713 VEGA | MGI Sequence Detail 2084 Not Applicable 
polypeptide OTTMUSP00000054804 VEGA | MGI Sequence Detail 473 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(586 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001611 Leucine-rich repeat
InterPro IPR003603 U2A'/phosphoprotein 32 family A, C-terminal
Protein Ontology PR:000009939 leucine-rich repeat-containing protein 6
References
(Earliest) J:61958 Xue JC, et al., Identification of a novel testis-specific leucine-rich protein in humans and mice. Biol Reprod. 2000 May;62(5):1278-84
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory