Btnl2
Gene Detail

Symbol Name ID

Btnl2 butyrophilin-like 2 MGI:1859549

Synonyms

BTL-II, BTLN2, butyrophylin-like MHC class II associated, NG9

Feature Type

protein coding gene

Genetic Map

Chromosome 17

17.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:34354822-34369493 bp, + strand From VEGA annotation of GRCm38   14672 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10482  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog

Gene Tree: Btnl2

Human homologs

Human Homolog		BTNL2, butyrophilin-like 2 (MHC class II associated)
NCBI Gene ID		56244
neXtProt AC		NX_Q9UIR0
Human Synonyms		BTL-II, HSBLMHC1, SS2
Human Chr (Location)		6p21.3; chr6:32362513-32374900 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human BTNL2

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (2 annotations)

Component

integral to membrane, membrane

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (48)    Tissues (47)   
Theiler Stages: 16, 17, 18, 28

Assay Type	Results
RT-PCR	48

cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000020172 (Evidence)
Ensembl Gene Model	ENSMUSG00000024340 (Evidence)
Entrez Gene	547431 (Evidence)
UniGene	441007
DFCI	TC1589769
DoTS	DT.522453
Consensus CDS Project	CCDS37585.1
International Mouse Knockout Project Status	Btnl2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020172	VEGA Gene Model | MGI Sequence Detail	14672	C57BL/6J
transcript	OTTMUST00000047932	VEGA | MGI Sequence Detail	2564	Not Applicable
polypeptide	OTTMUSP00000021847	VEGA | MGI Sequence Detail	514	Not Applicable

All sequences(22) RefSeq(3) UniProt(3)

Polymorphisms

SNPs(98 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR013162	CD80-like, immunoglobulin C2-set
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003599	Immunoglobulin subtype
InterPro	IPR013106	Immunoglobulin V-set
InterPro	IPR003596	Immunoglobulin V-set, subgroup
Protein Ontology	PR:000004849	butyrophilin-like protein 2

References

(Earliest) J:61935 Stammers M, et al., BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse. Immunogenetics. 2000 Apr;51(4-5):373-82
(Latest) J:192188 Zhao Y, et al., Cross-reactivity of anti-programmed death ligand 2 polyclonal antibody in mouse tissues. Sci China Life Sci. 2012 Nov;55(11):940-7
All references(26)

Other accession IDs

MGI:2685161