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Syt11
Gene Detail
 Symbol
Name
ID
Syt11
synaptotagmin XI
MGI:1859547
Synonyms 6530420C11Rik
Feature Type protein coding gene
Genetic Map
Chromosome 3
38.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:88744700-88775164 bp, - strand
From VEGA annotation of GRCm38

  30465 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23120  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: B/K protein/synaptotagmin
Gene Tree: Syt11

Human
homologs
Human Homolog SYT11, synaptotagmin XI
NCBI Gene ID 23208
neXtProt AC  NX_Q9BT88
Human Synonyms  SYT12, sytXI
Human Chr (Location)  1q21.2; chr1:155859469-155885199 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(15) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in no obvious abnormal phenotype.
 
Interactions
Syt11 interacts with 304 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process transport
Component cell junction, cytoplasmic vesicle, ...
Function calcium-dependent phospholipid binding, calcium ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (145)    Tissues (145)    Images (21)
Theiler Stages: 22, 23, 26, 28
Assay TypeResults
RNA in situ 145
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(14) Primer pair(1)
Microarray probesets(10)
Other database
links
VEGA Gene ModelOTTMUSG00000022625 (Evidence)
Ensembl Gene ModelENSMUSG00000068923 (Evidence)
Entrez Gene229521 (Evidence)
Consensus CDS ProjectCCDS38484.1
International Mouse Knockout Project StatusSyt11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022625 VEGA Gene Model | MGI Sequence Detail 30465 C57BL/6J ±  kb
transcript OTTMUST00000054196 VEGA | MGI Sequence Detail 5020 Not Applicable 
polypeptide OTTMUSP00000025831 VEGA | MGI Sequence Detail 430 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(8) UniProt(8)
Polymorphisms SNPs within 2kb(171 from dbSNP Build 137)    SNPs within 2kb including multiple locations(291)
Protein-related
information
ResourceIDDescription
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR001565 Synaptotagmin
Protein Ontology PR:000015896 synaptotagmin-11
References (Earliest) J:62060 Fukuda M, et al., Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X. J Biol Chem. 1999 Oct 29;274(44):31421-7
(Latest) J:211330 Milochau A, et al., Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. FEBS Lett. 2014 Jun 27;588(14):2217-22
All references(37)
Other
accession IDs
MGI:1923498, MGI:2139826

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/02/2014
MGI 5.19
The Jackson Laboratory