About   Help   FAQ
Rps28 Gene Detail
Summary
  • Symbol
    Rps28
  • Name
    ribosomal protein S28
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859516
    NCBI Gene: 54127
Location & Maps
more
  • Sequence Map
    Chr17:33819027-33824562 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5536 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RPS28, ribosomal protein S28
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RPS28, ribosomal protein S28
    Orthology source: HomoloGene
  • Synonyms
    DBA15, S28
  • Links
    NCBI Gene ID: 6234
    neXtProt AC: NX_P62857

  • Chr Location
    19p13.2; chr19:8321500-8322396 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human RPS28 associations

Human Disease Mouse Models
       Diamond-Blackfan Anemia 15 with Mandibulofacial Dysostosis; DBA15   OMIM: 606164
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    7 phenotype references
  • All Mutations and Alleles
    46
  • Gene trapped
    45
  • Targeted
    1
Mice homozygous for a gene trap allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037209 VEGA Gene Model | MGI Sequence Detail 5536 C57BL/6J ±  kb
transcript OTTMUST00000095941 VEGA | MGI Sequence Detail 437 Not Applicable  
polypeptide OTTMUSP00000053565 VEGA | MGI Sequence Detail 69 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    63 from dbSNP Build 137
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR012340 Nucleic acid-binding, OB-fold
    IPR000289 Ribosomal protein S28e
    IPR028626 Ribosomal protein S28e conserved site
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 11
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:29553 Hassouna N, et al., The complete nucleotide sequence of mouse 28S rRNA gene. Implications for the process of size increase of the large subunit rRNA in higher eukaryotes. Nucleic Acids Res. 1984 Apr 25;12(8):3563-83
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory