Atxn10
Gene Detail

Symbol Name ID

Atxn10 ataxin 10 MGI:1859293

Synonyms

E46, Sca10, TEG-169, Tex169

Feature Type

protein coding gene

Genetic Map

Chromosome 15

40.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr15:85336381-85463836 bp, + strand From NCBI annotation of GRCm38   127456 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40858  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Atxn10

Human homologs

Human Homolog		ATXN10, ataxin 10
NCBI Gene ID		25814
neXtProt AC		NX_Q9UBB4
Human Synonyms		E46L, HUMEEP, SCA10
Human Chr (Location)		22q13.31; chr22:46067678-46241187 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ATXN10

Alleles and phenotypes

All alleles(25) : Targeted(5) Gene trapped(20)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	nervous system development, neuron projection development
Component	cytoplasm, cytosol, ...
Function	identical protein binding, protein binding

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (29)    Tissues (29)    Images (8)
Theiler Stages: 19, 23, 28

Assay Type	Results
RNA in situ	29

cDNA source data(21)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(22) cDNA(22)
Microarray probesets(7)

Other database links

Ensembl Gene Model	ENSMUSG00000016541 (Evidence)
Entrez Gene	54138 (Evidence)
DFCI	TC1573101, TC1584723, TC1629329
DoTS	DT.101179375, DT.110829053, DT.111169931, DT.536939, DT.55256405, DT.94249838
NIA Mouse Gene Index	U043467
Consensus CDS Project	CCDS37170.1
International Mouse Knockout Project Status	Atxn10

Sequences

Length	Strain/Species
genomic	54138	NCBI Gene Model | MGI Sequence Detail	127456	C57BL/6J
transcript	NM_016843	RefSeq | MGI Sequence Detail	2425	C57BL/6
polypeptide	P28658	UniProt | EBI | MGI Sequence Detail	475	Not Applicable

All sequences(52) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(612 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011989	Armadillo-like helical
InterPro	IPR016024	Armadillo-type fold
InterPro	IPR019156	Ataxin-10 domain
Protein Ontology	PR:000004504	ataxin-10

Graphical View of Protein Domain Structure

References

(Earliest) J:35463 Lopez-Fernandez LA, et al., Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. Mamm Genome. 1996 Sep;7(9):698-700
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(40)

Other accession IDs

MGI:1096568, MGI:2145984, MGI:2146273