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Cldn6
Gene Detail
 Symbol
Name
ID
Cldn6
claudin 6
MGI:1859284
Feature Type protein coding gene
Genetic Map
Chromosome 17
11.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:23679365-23682446 bp, + strand
From VEGA annotation of GRCm38

  3082 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10300  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Cldn6

Human
homologs
Human Homolog CLDN6, claudin 6
NCBI Gene ID 9074
neXtProt AC  NX_P56747
Human Chr (Location)  16p13.3; chr16:3014712-3018187 (-)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Targeted(3) Gene trapped(3)
 
Mice homozygous for a null allele do not exhibit overt abnormalities.
 
Phenotype Images(3)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell-cell junction organization
Component cell junction, integral component of membrane, ...
Function protein binding, structural molecule activity
External Resources: FuncBase
Expression
Literature Summary: (18 records)
Data Summary: Results (159)    Tissues (134)    Images (36)
Theiler Stages: 9, 11, 13, 14, 15, 17, 18, 19, 20, 21, 22, 23, 24, 25, 28
Assay TypeResults
Immunohistochemistry 19
RNA in situ 114
Western blot 1
RT-PCR 25
cDNA source data(44)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(48) cDNA(44) Primer pair(2) Other(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000033036 (Evidence)
Ensembl Gene ModelENSMUSG00000023906 (Evidence)
Entrez Gene54419 (Evidence)
UniGene86421
DFCITC1580046
DoTSDT.531329, DT.55212758, DT.94028242
NIA Mouse Gene IndexU017617
Consensus CDS ProjectCCDS28457.1
International Mouse Knockout Project StatusCldn6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033036 VEGA Gene Model | MGI Sequence Detail 3082 C57BL/6J ±  kb
transcript OTTMUST00000082451 VEGA | MGI Sequence Detail 1506 Not Applicable 
polypeptide OTTMUSP00000044180 VEGA | MGI Sequence Detail 219 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(14 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006187 Claudin
InterPro IPR003925 Claudin-6
InterPro IPR017974 Claudin, conserved site
InterPro IPR004031 PMP-22/EMP/MP20/Claudin
Protein Ontology PR:000005554 claudin-6
References (Earliest) J:58914 Itoh M, et al., Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol. 1999 Dec 13;147(6):1351-63
(Latest) J:199239 Magnuson MA, et al., Pancreas-specific cre driver lines and considerations for their prudent use. Cell Metab. 2013 Jul 2;18(1):9-20
All references(59)
Other
accession IDs
MGI:2146955

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory