About   Help   FAQ
Dctn3 Gene Detail
Summary
  • Symbol
    Dctn3
  • Name
    dynactin 3
  • Synonyms
    p24
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859251
    NCBI Gene: 53598
  • Gene Overview
    MyGene.info: DCTN3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:41714798-41723163 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 21.98 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    54 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859251
protein coding gene Chr4:41714798-41723170 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028169
protein coding gene Chr4:39680581-39688953 (-)
A/J MGP_AJ_G0028127
protein coding gene Chr4:38168396-38176767 (-)
AKR/J MGP_AKRJ_G0028090
protein coding gene Chr4:39159892-39168280 (-)
BALB/cJ MGP_BALBcJ_G0028140
protein coding gene Chr4:38513583-38521971 (-)
C3H/HeJ MGP_C3HHeJ_G0027878
protein coding gene Chr4:39750416-39759139 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028581
protein coding gene Chr4:41177032-41185404 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025920
protein coding gene Chr4:35815676-35823710 (-)
CAST/EiJ MGP_CASTEiJ_G0027323
protein coding gene Chr4:39396171-39404554 (-)
CBA/J MGP_CBAJ_G0027840
protein coding gene Chr4:42541523-42549895 (-)
DBA/2J MGP_DBA2J_G0027984
protein coding gene Chr4:38099159-38107531 (-)
FVB/NJ MGP_FVBNJ_G0027951
protein coding gene Chr4:37419129-37427438 (-)
LP/J MGP_LPJ_G0028092
protein coding gene Chr4:39770479-39778851 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027983
protein coding gene Chr4:45857886-45866274 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028639
protein coding gene Chr4:39271729-39280097 (-)
PWK/PhJ MGP_PWKPhJ_G0027042
protein coding gene Chr4:38136128-38144844 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026869
protein coding gene Chr4:39001161-39009562 (-)
WSB/EiJ MGP_WSBEiJ_G0027399
protein coding gene Chr4:39256884-39265260 (-)



Homology
more
  • Human Ortholog
    DCTN3, dynactin subunit 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DCTN3, dynactin subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DCTN22, DCTN-22
  • Links
    NCBI Gene ID: 11258
    neXtProt AC: NX_O75935
    UniProt: O75935

  • Chr Location
    9p13.3; chr9:34613545-34620523 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically and radiation induced
    1
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Dctn3
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 53598 NCBI Gene Model | MGI Sequence Detail 8366 C57BL/6J ±  kb
transcript NM_016890 RefSeq | MGI Sequence Detail 966 C57BL/6  
polypeptide Q9Z0Y1 UniProt | EBI | MGI Sequence Detail 186 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 101
    cDNA 101

    Microarray probesets 4
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:62147 Pfister KK, et al., Identification and molecular characterization of the p24 dynactin light chain. Cell Motil Cytoskeleton. 1998;41(2):154-67
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory