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Cacng6 Gene Detail
Summary
  • Symbol
    Cacng6
  • Name
    calcium channel, voltage-dependent, gamma subunit 6
  • Synonyms
    2310033H20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859168
    NCBI Gene: 54378
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:3472711-3484183 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 2.00 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    115 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859168
protein coding gene Chr7:3472017-3484183 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031519
protein coding gene Chr7:343696-355095 (+)
A/J MGP_AJ_G0031494
protein coding gene Chr7:333834-345237 (+)
AKR/J MGP_AKRJ_G0031422
protein coding gene Chr7:328391-339772 (+)
BALB/cJ MGP_BALBcJ_G0031502
protein coding gene Chr7:334680-346478 (+)
C3H/HeJ MGP_C3HHeJ_G0031222
protein coding gene Chr7:343017-354430 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031962
protein coding gene Chr7:348649-359998 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029089
protein coding gene Chr7:229535-241194 (+)
CAST/EiJ MGP_CASTEiJ_G0030591
protein coding gene Chr7:337634-350221 (+)
CBA/J MGP_CBAJ_G0031182
protein coding gene Chr7:450557-464812 (+)
DBA/2J MGP_DBA2J_G0031339
protein coding gene Chr7:325412-336891 (+)
FVB/NJ MGP_FVBNJ_G0031291
protein coding gene Chr7:322403-334453 (+)
LP/J MGP_LPJ_G0031424
protein coding gene Chr7:343089-363121 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031330
protein coding gene Chr7:375578-387862 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031996
protein coding gene Chr7:324145-336493 (+)
PWK/PhJ MGP_PWKPhJ_G0030318
protein coding gene Chr7:468587-480855 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030142
protein coding gene Chr7:399693-411117 (+)
WSB/EiJ MGP_WSBEiJ_G0030685
protein coding gene Chr7:333578-344869 (+)



Homology
more
  • Human Ortholog
    CACNG6, calcium voltage-gated channel auxiliary subunit gamma 6
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CACNG6, calcium voltage-gated channel auxiliary subunit gamma 6
  • Links
    NCBI Gene ID: 59285
    neXtProt AC: NX_Q9BXT2
    UniProt: Q9BXT2

  • Chr Location
    19q13.42; chr19:53991149-54012666 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human CACNG6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078815 Ensembl Gene Model | MGI Sequence Detail 11473 C57BL/6J ±  kb
transcript ENSMUST00000183200 Ensembl | MGI Sequence Detail 1977 Not Applicable  
polypeptide ENSMUSP00000138622 Ensembl | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000004955 voltage-dependent calcium channel gamma-6 subunit
  • InterPro Domains
    IPR004031 PMP-22/EMP/MP20/Claudin
    IPR008370 Voltage-dependent calcium channel, gamma-6 subunit
    IPR008368 Voltage-dependent calcium channel, gamma subunit
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1916809, MGI:2142197
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:61323 Klugbauer N, et al., A family of gamma-like calcium channel subunits. FEBS Lett. 2000 Mar 24;470(2):189-97
  • Latest
    J:344312 Liu H, et al., Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory