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Pabpn1
Gene Detail
 Symbol
Name
ID
Pabpn1
poly(A) binding protein, nuclear 1
MGI:1859158
Synonyms Pabp3, poly(A) binding protein II
Feature Type protein coding gene
Genetic Map
Chromosome 14
27.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:54892500-54898169 bp, + strand
From VEGA annotation of GRCm38

  5670 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3412  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog

Gene Tree: Pabpn1

Human
homologs
Human Homolog PABPN1, poly(A) binding protein, nuclear 1
NCBI Gene ID 8106
neXtProt AC  NX_Q86U42
Human Synonyms  OPMD, PAB2, PABII, PABP2, PABP-2
Human Chr (Location)  14q11.2; chr14:23320188-23326185 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PABPN1
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Interactions
Pabpn1 interacts with 181 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process mRNA polyadenylation, mRNA processing, ...
Component cytoplasm, nucleus, ...
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (66)    Tissues (52)    Images (16)
Theiler Stages: 19, 21, 23, 27, 28
Assay TypeResults
RNA in situ 64
RT-PCR 2
cDNA source data(171)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(172) cDNA(171) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000037620 (Evidence)
Ensembl Gene ModelENSMUSG00000022194 (Evidence)
Entrez Gene54196 (Evidence)
UniGene7723
DFCITC1576661
DoTSDT.101400669, DT.101400674, DT.40160526, DT.94358789
NIA Mouse Gene IndexU015637
Consensus CDS ProjectCCDS27104.1
International Mouse Knockout Project StatusPabpn1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037620 VEGA Gene Model | MGI Sequence Detail 5670 C57BL/6J ±  kb
transcript OTTMUST00000081723 VEGA | MGI Sequence Detail 1775 Not Applicable 
polypeptide OTTMUSP00000054340 VEGA | MGI Sequence Detail 319 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(4) UniProt(7)
Polymorphisms RFLP(1) : SNPs within 2kb(64 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000012210 polyadenylate-binding protein 2
References (Earliest) J:44882 Lee YJ, et al., Genomic structure and expression of murine poly(A) binding protein II gene. Biochim Biophys Acta. 1998 Jan 7;1395(1):40-6
(Latest) J:199679 de Klerk E, et al., Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation. Nucleic Acids Res. 2012 Oct;40(18):9089-101
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory