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Batf
Gene Detail
Symbol

Name
ID
Batf
basic leucine zipper transcription factor, ATF-like
MGI:1859147
Synonyms
B-ATF, SFA-2
Feature Type
protein coding gene
Genetic Map
Chromosome 12
39.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:85686669-85709087 bp, + strand
From VEGA annotation of GRCm38

  22419 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4666  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: BATF
Gene Tree: Batf

Human
homologs
BATF, basic leucine zipper transcription factor, ATF-like
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10538
neXtProt AC: NX_Q16520

Human Synonyms: B-ATF, BATF1, SFA2, SFA-2

Human Chr (Location): 14q24.3; chr14:75522441-75546992 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(3) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygote null mice are defective in generation of Th17 T cells.
 
Interactions
Batf interacts with 38 markers (Mir30c-1, Mir30c-2, Mir101c, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process cell differentiation, cellular response to DNA damage stimulus, ...
Component cytoplasm, intracellular, ...
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (139)    Tissues (139)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 139
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA BATF    NEW 
Molecular
reagents
All nucleic(16) Genomic(1) cDNA(15)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000016692 (Evidence)
Ensembl Gene Model ENSMUSG00000034266 (Evidence)
Entrez Gene 53314 (Evidence)
UniGene 6672
DFCI TC1583999
DoTS DT.529933
NIA Mouse Gene Index U014213
Consensus CDS Project CCDS26061.1
International Mouse Phenotyping Consortium Status Batf
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016692 VEGA Gene Model | MGI Sequence Detail 22419 C57BL/6J ±  kb
transcript OTTMUST00000040432 VEGA | MGI Sequence Detail 955 Not Applicable 
polypeptide OTTMUSP00000018061 VEGA | MGI Sequence Detail 125 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(140 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR000837 Fos transforming protein
Protein Ontology PR:000004654 basic leucine zipper transcriptional factor ATF-like
References
(Earliest) J:62034 Williams KL, et al., Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus. Eur J Immunol. 2001 May;31(5):1620-7
(Latest) J:209881 Kurachi M, et al., The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells. Nat Immunol. 2014 Apr;15(4):373-83
All references(47)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory