Batf
Gene Detail

Symbol Name ID

Batf basic leucine zipper transcription factor, ATF-like MGI:1859147

Synonyms

B-ATF, SFA-2

Feature Type

protein coding gene

Genetic Map

Chromosome 12

39.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr12:85686669-85709087 bp, + strand From VEGA annotation of GRCm38   22419 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4666  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Batf

Human homologs

Human Homolog		BATF, basic leucine zipper transcription factor, ATF-like
NCBI Gene ID		10538
neXtProt AC		NX_Q16520
Human Synonyms		B-ATF, BATF1, SFA2, SFA-2
Human Chr (Location)		14q24.3; chr14:75988784-76013335 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(8) : Targeted(5) Gene trapped(3)
 

Homozygote null mice are defective in generation of Th17 T cells.

 

Gene Ontology (GO) classifications

All GO classifications: (24 annotations)

Process	cell differentiation, cytokine production, ...
Component	cytoplasm, nucleus
Function	DNA binding, protein binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (139)    Tissues (139)    Images (5)
Theiler Stages: 17, 18, 21, 22, 23, 28

Assay Type	Results
RNA in situ	139

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(16) Genomic(1) cDNA(15)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000016692 (Evidence)
Ensembl Gene Model	ENSMUSG00000034266 (Evidence)
Entrez Gene	53314 (Evidence)
UniGene	6672
DFCI	TC1583999
DoTS	DT.529933
NIA Mouse Gene Index	U014213
Consensus CDS Project	CCDS26061.1
International Mouse Knockout Project Status	Batf

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016692	VEGA Gene Model | MGI Sequence Detail	22419	C57BL/6J
transcript	OTTMUST00000040432	VEGA | MGI Sequence Detail	955	Not Applicable
polypeptide	OTTMUSP00000018061	VEGA | MGI Sequence Detail	125	Not Applicable

All sequences(17) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(132 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004827	Basic-leucine zipper domain
InterPro	IPR000837	Fos transforming protein
Protein Ontology	PR:000004654	basic leucine zipper transcriptional factor ATF-like

References

(Earliest) J:62034 Williams KL, et al., Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus. Eur J Immunol. 2001 May;31(5):1620-7
(Latest) J:190258 Wang J, et al., A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell. 2012 Mar 2;148(5):1001-14
All references(43)