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Elp5 Gene Detail
Summary
  • Symbol
    Elp5
  • Name
    elongator acetyltransferase complex subunit 5
  • Synonyms
    Clone 13u, Rai12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859017
    NCBI Gene: 54351
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69859050-69872352 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.94 cM, cytoband B4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    65 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859017
 protein coding gene Chr11:69859048-69873343 (-)
129S1/SvImJ ENSMUSG00200049382
 protein coding gene Chr11:66806039-66820333 (-)
A/J ENSMUSG00195040821
 protein coding gene Chr11:66832507-66846802 (-)
AKR/J ENSMUSG00220054080
 protein coding gene Chr11:66941504-66955800 (-)
BALB/cJ ENSMUSG00180036074
 protein coding gene Chr11:66901057-66915351 (-)
C3H/HeJ ENSMUSG00175053817
 protein coding gene Chr11:66851250-66865544 (-)
C57BL/6NJ ENSMUSG00215052044
 protein coding gene Chr11:66628414-66642711 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016609
 protein coding gene Chr11:64718135-64731789 (-)
CAST/EiJ ENSTCUG00005053236
 protein coding gene Chr11:66394443-66408499 (-)
CBA/J ENSMUSG00210054280
 protein coding gene Chr11:66705327-66719621 (-)
DBA/2J ENSMUSG00185041511
 protein coding gene Chr11:66907659-66921882 (-)
FVB/NJ ENSMUSG00205053063
 protein coding gene Chr11:66799348-66813616 (-)
JF1/MsJ ENSUMUG00000050796
 protein coding gene Chr11:67306089-67320312 (-)
LP/J ENSMUSG00230053659
 protein coding gene Chr11:68016379-68030673 (-)
NOD/ShiLtJ ENSMUSG00190053910
 protein coding gene Chr11:66935264-66949558 (-)
NZO/HlLtJ ENSMUSG00225043919
 protein coding gene Chr11:70197825-70212119 (-)
PWK/PhJ ENSLUMG00010053245
 protein coding gene Chr11:66821420-66835641 (-)
SPRET/EiJ ENSMSPG00010045447
 protein coding gene Chr11:67551165-67564961 (-)
WSB/EiJ ENSIUOG00005047521
 protein coding gene Chr11:66836691-66850975 (-)



Homology
more
  • Human Ortholog
    ELP5, elongator acetyltransferase complex subunit 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ELP5, elongator acetyltransferase complex subunit 5
  • Synonyms
    C17orf81, DERP6, HSPC002, MST071, MSTP071
  • Links
    NCBI Gene ID: 23587
    UniProt: Q8TE02

  • Chr Location
    17p13.1; chr17:7250823-7260165 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    14
  • Targeted
    3
  • Genomic Mutations
    2 involving Elp5
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    628
  • Tissues
    20
  • cDNA Data
    139
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54351 NCBI Gene Model | MGI Sequence Detail 13303 C57BL/6J ±  kb
transcript NM_018740 RefSeq | MGI Sequence Detail 1461 C57BL/6  
polypeptide Q99L85 UniProt | EBI | MGI Sequence Detail 300 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 139
    cDNA 139
    Antibodies 1

    Microarray probesets 3
References
more
  • Summaries
    All 46
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:380820 Jaciuk M, et al., Cryo-EM structure of the fully assembled Elongator complex. Nucleic Acids Res. 2023 Mar 21;51(5):2011-2032
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory