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Ddah2 Gene Detail
Summary
  • Symbol
    Ddah2
  • Name
    dimethylarginine dimethylaminohydrolase 2
  • Synonyms
    Clone 7u, Ddah, G6a, NG30
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859016
    NCBI Gene: 51793
Location & Maps
more
  • Sequence Map
    Chr17:35059035-35062095 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3061 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.59 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DDAH2, dimethylarginine dimethylaminohydrolase 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DDAH2, dimethylarginine dimethylaminohydrolase 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DDAH, DDAHII, G6a, HEL-S-277, NG30
  • Links
    NCBI Gene ID: 23564
    neXtProt AC: NX_O95865

  • Chr Location
    6p21.3; chr6:31727037-31730265 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
  • All Mutations and Alleles
    8
  • Gene trapped
    3
  • Targeted
    5
  • Incidental Mutations
Mice exhibit normal embryonic survival.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037923 VEGA Gene Model | MGI Sequence Detail 3061 C57BL/6J ±  kb
transcript OTTMUST00000097748 VEGA | MGI Sequence Detail 1342 Not Applicable  
polypeptide OTTMUSP00000054824 VEGA | MGI Sequence Detail 285 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006339 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
  • EC
  • InterPro Domains
    IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase
    IPR033202 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
Molecular
Reagents
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  • All nucleic 162
    Genomic 1
    cDNA 161

    Microarray probesets 3
Other
Accession IDs
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MGI:2146979, MGI:2147062
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:44498 Spanjaard RA, et al., Clone 10d/BM28 (CDCL1), an early S-phase protein, is an important growth regulator of melanoma. Cancer Res. 1997 Nov 15;57(22):5122-8
  • Latest
    J:173535 Pullamsetti SS, et al., The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis. Sci Transl Med. 2011 Jun 15;3(87):87ra53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory