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Atf7ip Gene Detail
Summary
  • Symbol
    Atf7ip
  • Name
    activating transcription factor 7 interacting protein
  • Synonyms
    2610204M12Rik, AM, ATFa-associated Modulator, Mcaf1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858965
    NCBI Gene: 54343
  • Gene Overview
    MyGene.info: ATF7IP
Location & Maps
more
  • Sequence Map
    Chr6:136506167-136610862 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      104696 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ATF7IP, activating transcription factor 7 interacting protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ATF7IP, activating transcription factor 7 interacting protein
    Orthology source: HomoloGene
  • Synonyms
    AM, ATF-IP, MCAF, MCAF1, p621
  • Links
    NCBI Gene ID: 55729
    neXtProt AC: NX_Q6VMQ6

  • Chr Location
    12p13.1; chr12:14365632-14502935 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000047948 VEGA Gene Model | MGI Sequence Detail 104696 C57BL/6J ±  kb
transcript OTTMUST00000123287 VEGA | MGI Sequence Detail 8059 Not Applicable  
polypeptide OTTMUSP00000067369 VEGA | MGI Sequence Detail 1306 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    905 from dbSNP Build 142
Protein
Information
less
  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000004405 activating transcription factor 7-interacting protein 1
  • InterPro Domains
    IPR026085 Activating transcription factor 7-interacting protein
    IPR031870 ATF7-interacting protein , protein binding domain
    IPR003961 Fibronectin type III
    IPR013783 Immunoglobulin-like fold
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 7
Other
Accession IDs
less
MGI:1919738
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:61657 De Graeve F, et al., A murine ATFa-associated factor with transcriptional repressing activity. Oncogene. 2000 Mar 30;19(14):1807-19
  • Latest
    J:209441 Waterfield M, et al., The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. Nat Immunol. 2014 Mar;15(3):258-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory