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Actr1a Gene Detail
Summary
  • Symbol
    Actr1a
  • Name
    ARP1 actin-related protein 1A, centractin alpha
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858964
    NCBI Gene: 54130
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:46365252-46384180 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    210 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858964
protein coding gene Chr19:46365250-46384187 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025208
protein coding gene Chr19:46063871-46084142 (-)
A/J MGP_AJ_G0025184
protein coding gene Chr19:43795883-43814485 (-)
AKR/J MGP_AKRJ_G0025153
protein coding gene Chr19:45216486-45235483 (-)
BALB/cJ MGP_BALBcJ_G0025179
protein coding gene Chr19:43852234-43870868 (-)
C3H/HeJ MGP_C3HHeJ_G0024939
protein coding gene Chr19:45381165-45401998 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025622
protein coding gene Chr19:47211552-47230630 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023036
protein coding gene Chr19:43033046-43051793 (-)
CAST/EiJ MGP_CASTEiJ_G0024404
protein coding gene Chr19:45179198-45203213 (-)
CBA/J MGP_CBAJ_G0024919
protein coding gene Chr19:49570325-49592441 (-)
DBA/2J MGP_DBA2J_G0025051
protein coding gene Chr19:43616349-43635080 (-)
FVB/NJ MGP_FVBNJ_G0025012
protein coding gene Chr19:43397875-43416811 (-)
LP/J MGP_LPJ_G0025137
protein coding gene Chr19:45972141-45991960 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025043
protein coding gene Chr19:48912879-48936054 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025680
protein coding gene Chr19:45322241-45342842 (-)
PWK/PhJ MGP_PWKPhJ_G0024153
protein coding gene Chr19:43564139-43583558 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023957
protein coding gene Chr19:43973350-43997361 (-)
WSB/EiJ MGP_WSBEiJ_G0024474
protein coding gene Chr19:45463274-45485244 (-)



Homology
more
  • Human Ortholog
    ACTR1A, actin related protein 1A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACTR1A, actin related protein 1A
  • Synonyms
    ARP1, Arp1A, CTRN1
  • Links
    NCBI Gene ID: 10121
    neXtProt AC: NX_P61163
    UniProt: P61163

  • Chr Location
    10q24.32; chr10:102461881-102502712 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 54130 NCBI Gene Model | MGI Sequence Detail 18929 C57BL/6J ±  kb
transcript NM_016860 RefSeq | MGI Sequence Detail 2766 C57BL/6  
polypeptide P61164 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 257
    cDNA 257

    Microarray probesets 6
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:57581 Kusano K, et al., Primary structure of mouse actin-related protein 1 (Arp1) and its tissue expression. Zoolog Sci. 1997 Feb;14(1):77-82
  • Latest
    J:282974 Lee M, et al., Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain. J Cell Biol. 2020 Feb 3;219(2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory