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Elovl2
Gene Detail
Symbol

Name
ID
Elovl2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
MGI:1858960
Synonyms
Ssc2
Feature Type
protein coding gene
Genetic Map
Chromosome 13
20.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:41182495-41220405 bp, - strand
From VEGA annotation of GRCm38

  37911 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23042  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ELOVL2
Gene Tree: Elovl2

Human
homologs
ELOVL2, ELOVL fatty acid elongase 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 54898
neXtProt AC: NX_Q9NXB9

Human Synonyms: SSC2

Human Chr (Location): 6p24.2; chr6:10980759-11044391 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice heterozygous for a knock-out allele exhibit reduced male fertility. Mice homozygous for a knock-out allele exhibit male infertility associated with arrested spermatogenesis.
 
Interactions
Elovl2 interacts with 338 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (9 records)
Data Summary: Results (210)    Tissues (123)    Images (38)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 208
RT-PCR 2
cDNA source data(44)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase elovl2 ; ZFIN elovl2    NEW 
Molecular
reagents
All nucleic(45) cDNA(44) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000029813 (Evidence)
Ensembl Gene Model ENSMUSG00000021364 (Evidence)
Entrez Gene 54326 (Evidence)
UniGene 2567
DFCI TC1714794, TC1577439
DoTS DT.97408703, DT.489418
NIA Mouse Gene Index U034713
EC 2.3.1.199
Consensus CDS Project CCDS36639.1
International Mouse Phenotyping Consortium Status Elovl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029813 VEGA Gene Model | MGI Sequence Detail 37911 C57BL/6J ±  kb
transcript OTTMUST00000074002 VEGA | MGI Sequence Detail 3726 Not Applicable 
polypeptide OTTMUSP00000038380 VEGA | MGI Sequence Detail 292 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(375 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002076 GNS1/SUR4 membrane protein
Protein Ontology PR:000007037 elongation of very long chain fatty acids protein 2
References
(Earliest) J:61900 Tvrdik P, et al., Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids. J Cell Biol. 2000 May 1;149(3):707-18
(Latest) J:216600 Lau CG, et al., Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil. Mol Reprod Dev. 2014 Nov;81(11):994-1008
All references(39)
Other
accession IDs
MGI:2145206

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory