Sept1
Gene Detail

Symbol Name ID

Sept1 septin 1 MGI:1858916

Synonyms

Diff6, PNUTL3

Feature Type

protein coding gene

Genetic Map

Chromosome 7

69.39 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:127214447-127218498 bp, - strand From VEGA annotation of GRCm38   4052 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:23009  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: septin
Gene Tree: Sept1

Human homologs

Human Homolog		SEPT1, septin 1
NCBI Gene ID		1731
neXtProt AC		NX_Q8WYJ6
Human Synonyms		DIFF6, LARP, PNUTL3, SEP1
Human Chr (Location)		16p11.1; chr16:30389454-30394171 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(61) : Targeted(2) Gene trapped(59)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	cell cycle, cell division
Component	cytoplasm, cytoskeleton, ...
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (4)    Tissues (1)    Images (4)
Theiler Stages: 23

Assay Type	Results
RNA in situ	4

cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(22) cDNA(22)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000022181 (Evidence)
Ensembl Gene Model	ENSMUSG00000000486 (Evidence)
Entrez Gene	54204 (Evidence)
UniGene	18
DFCI	TC1585457, TC1670226, TC1708758
DoTS	DT.101354157, DT.532363, DT.94307822
Consensus CDS Project	CCDS40141.1
International Mouse Knockout Project Status	Sept1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022181	VEGA Gene Model | MGI Sequence Detail	4052	C57BL/6J
transcript	OTTMUST00000052670	VEGA | MGI Sequence Detail	1486	Not Applicable
polypeptide	OTTMUSP00000025010	VEGA | MGI Sequence Detail	366	Not Applicable

All sequences(47) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(45 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000038	Cell division protein GTP binding
InterPro	IPR016491	Septin
Protein Ontology	PR:000014648	septin-1

References

(Earliest) J:25671 Nottenburg C, et al., Lymphocyte HEV adhesion variants differ in the expression of multiple gene sequences. Gene. 1990 Nov 15;95(2):279-84
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(33)