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Sept1
Gene Detail
Symbol

Name
ID
Sept1
septin 1
MGI:1858916
Synonyms
Diff6, PNUTL3
Feature Type
protein coding gene
Genetic Map
Chromosome 7
69.39 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:127214447-127218498 bp, - strand
From VEGA annotation of GRCm38

  4052 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23009  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: septin
Gene Tree: Sept1

Human
homologs
Human Homolog SEPT1, septin 1
NCBI Gene ID 1731
neXtProt AC  NX_Q8WYJ6
Human Synonyms  DIFF6, LARP, PNUTL3, SEP1
Human Chr (Location)  16p11.1; chr16:30378133-30382850 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(63) : Gene trapped(59) Targeted(4)
Genomic Mutations involving Sept1 (2)
Alleles Annotated to Human Diseases(1)   
Interactions
Sept1 interacts with 60 markers (Mir29b-1, Mir29b-2, Mir92-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell cycle, cell division, ...
Component cell, cytoplasm, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (4)    Tissues (1)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 4
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022181 (Evidence)
Ensembl Gene ModelENSMUSG00000000486 (Evidence)
Entrez Gene54204 (Evidence)
UniGene18
DFCITC1585457, TC1670226, TC1708758
DoTSDT.94307822, DT.532363, DT.101354157
Consensus CDS ProjectCCDS40141.1
International Mouse Knockout Project StatusSept1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022181 VEGA Gene Model | MGI Sequence Detail 4052 C57BL/6J ±  kb
transcript OTTMUST00000052670 VEGA | MGI Sequence Detail 1486 Not Applicable 
polypeptide OTTMUSP00000025010 VEGA | MGI Sequence Detail 366 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(10) UniProt(5)
Polymorphisms
SNPs within 2kb(60 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000038 Cell division protein GTP binding
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016491 Septin
Protein Ontology PR:000014648 septin-1
References
(Earliest) J:25671 Nottenburg C, et al., Lymphocyte HEV adhesion variants differ in the expression of multiple gene sequences. Gene. 1990 Nov 15;95(2):279-84
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory