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Rundc3a Gene Detail
Summary
  • Symbol
    Rundc3a
  • Name
    RUN domain containing 3A
  • Synonyms
    Rap2ip, Rpip8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858752
    NCBI Gene: 51799
  • Gene Overview
    MyGene.info: RUNDC3A
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:102393403-102402555 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 66.29 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    9 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858752
protein coding gene Chr11:102393403-102402939 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019233
protein coding gene Chr11:105363606-105372752 (+)
A/J MGP_AJ_G0019201
protein coding gene Chr11:100921447-100930598 (+)
AKR/J MGP_AKRJ_G0019170
protein coding gene Chr11:104039170-104048322 (+)
BALB/cJ MGP_BALBcJ_G0019175
protein coding gene Chr11:101403298-101412444 (+)
C3H/HeJ MGP_C3HHeJ_G0018984
protein coding gene Chr11:104244841-104253987 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019624
protein coding gene Chr11:108657221-108666373 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017250
protein coding gene Chr11:98347573-98356938 (+)
CAST/EiJ MGP_CASTEiJ_G0018538
protein coding gene Chr11:105237849-105247012 (+)
CBA/J MGP_CBAJ_G0018953
protein coding gene Chr11:113142164-113151316 (+)
DBA/2J MGP_DBA2J_G0019065
protein coding gene Chr11:100436076-100445222 (+)
FVB/NJ MGP_FVBNJ_G0019055
protein coding gene Chr11:99968247-99977399 (+)
LP/J MGP_LPJ_G0019134
protein coding gene Chr11:105887301-105896447 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019086
protein coding gene Chr11:112637052-112646204 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019662
protein coding gene Chr11:104408320-104417472 (+)
PWK/PhJ MGP_PWKPhJ_G0018301
protein coding gene Chr11:101504424-101513585 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018093
protein coding gene Chr11:104164959-104174110 (+)
WSB/EiJ MGP_WSBEiJ_G0018587
protein coding gene Chr11:104404044-104413196 (+)



Homology
more
  • Human Ortholog
    RUNDC3A, RUN domain containing 3A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RUNDC3A, RUN domain containing 3A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RAP2IP, RPIP8, RPIP-8
  • Links
    NCBI Gene ID: 10900
    neXtProt AC: NX_Q59EK9
    UniProt: Q59EK9

  • Chr Location
    17q21.31; chr17:44308559-44318670 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006575 Ensembl Gene Model | MGI Sequence Detail 9153 C57BL/6J ±  kb
transcript ENSMUST00000006750 Ensembl | MGI Sequence Detail 2046 Not Applicable  
polypeptide ENSMUSP00000006750 Ensembl | MGI Sequence Detail 446 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 6
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:60992 Janoueix-Lerosey I, et al., Identification of a specific effector of the small GTP-binding protein Rap2. Eur J Biochem. 1998 Mar 1;252(2):290-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory