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Kat6b
Gene Detail
 Symbol
Name
ID
Kat6b
K(lysine) acetyltransferase 6B
MGI:1858746
Synonyms B130044K16Rik, monocytic leukemia, Morf, Myst4, qkf, querkopf
Feature Type protein coding gene
Genetic Map
Chromosome 14
11.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:21481434-21672478 bp, + strand
From VEGA annotation of GRCm38

  191045 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136480  Vertebrate Homology Class
1 mouse; 1 rat

Gene Tree: Kat6b

Mutations,
alleles, and
phenotypes
All mutations/alleles(222) : Gene trapped(222)
Incidental mutations (data from APF )
 
Reduced expression of this gene results in developmental defects of the skeleton and brain, particularly the cerebral cortex.
 
Interactions
Kat6b interacts with 344 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process chromatin modification, histone acetylation, ...
Component chromosome, nucleosome, ...
Function DNA binding, histone acetyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (74)    Tissues (40)    Images (4)
Theiler Stages: 2, 3, 4, 5, 17, 18, 19, 21, 23, 28
Assay TypeResults
RNA in situ 30
RT-PCR 44
cDNA source data(123)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(125) cDNA(123) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000043207 (Evidence)
Ensembl Gene ModelENSMUSG00000021767 (Evidence)
Entrez Gene54169 (Evidence)
UniGene248967
DFCITC1575109, TC1588777, TC1593447, TC1617155, TC1620857, TC1703381, TC1759300, TC1773225
DoTSDT.101134843, DT.101401316, DT.101401318, DT.101737527, DT.101737530, DT.102557193, DT.487606, DT.91327092, DT.91362374
NIA Mouse Gene IndexU015372
EC2.3.1.48
Consensus CDS ProjectCCDS59615.1
International Mouse Knockout Project StatusKat6b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000043207 VEGA Gene Model | MGI Sequence Detail 191045 C57BL/6J ±  kb
transcript OTTMUST00000113320 VEGA | MGI Sequence Detail 7660 Not Applicable 
polypeptide OTTMUSP00000063398 VEGA | MGI Sequence Detail 1872 Not Applicable 

For the selected sequences
All sequences(105) RefSeq(22) UniProt(7)
Polymorphisms SNPs within 2kb(1037 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1039)
Protein-related
information
ResourceIDDescription
InterPro IPR016181 Acyl-CoA N-acyltransferase
InterPro IPR005818 Histone H1/H5
InterPro IPR002717 MOZ/SAS-like protein
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000010891 histone acetyltransferase KAT6B
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:197289 Sheikh BN, et al., Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells. J Cell Sci. 2012 Jan 15;125(Pt 2):295-309
All references(48)
Other
accession IDs
MGI:2145668, MGI:2443197

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory