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Vamp4
Gene Detail
 Symbol
Name
ID
Vamp4
vesicle-associated membrane protein 4
MGI:1858730
Synonyms D1Ertd147e
Feature Type protein coding gene
Genetic Map
Chromosome 1
70.29 cM, cytoband H1
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr1:162570515-162599084 bp, + strand
From VEGA annotation of GRCm38

  28570 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37847  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: synaptobrevin
Gene Tree: Vamp4

Human
homologs
Human Homolog VAMP4, vesicle-associated membrane protein 4
NCBI Gene ID 8674
neXtProt AC  NX_O75379
Human Synonyms  VAMP24, VAMP-4
Human Chr (Location)  1q24-q25; chr1:171700156-171742239 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(10)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Vamp4 interacts with 271 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process exocytosis, Golgi to plasma membrane protein transport, ...
Component cell, cell surface, ...
Function SNAP receptor activity, SNARE binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (6)    Tissues (6)    Images (4)
Theiler Stages: 21, 28
Assay TypeResults
Immunohistochemistry 6
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000033107 (Evidence)
Ensembl Gene ModelENSMUSG00000026696 (Evidence)
Entrez Gene53330 (Evidence)
DFCITC1579600, TC1583008, TC1605359
DoTSDT.481843, DT.530798
PDB2NPS
Consensus CDS ProjectCCDS15421.1
International Mouse Knockout Project StatusVamp4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033107 VEGA Gene Model | MGI Sequence Detail 28570 C57BL/6J ±  kb
transcript OTTMUST00000082753 VEGA | MGI Sequence Detail 901 Not Applicable 
polypeptide OTTMUSP00000044396 VEGA | MGI Sequence Detail 141 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(345 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001388 Synaptobrevin
InterPro IPR016444 Synaptobrevin, metazoa/fungi
Protein Ontology PR:000017251 vesicle-associated membrane protein 4
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:198881 Lei N, et al., Flightless, secreted through a late endosome/lysosome pathway, binds LPS and dampens cytokine secretion. J Cell Sci. 2012 Sep 15;125(Pt 18):4288-96
All references(42)
Other
accession IDs
MGI:1098701

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory