About   Help   FAQ
Copg1 Gene Detail
Summary
  • Symbol
    Copg1
  • Name
    coatomer protein complex, subunit gamma 1
  • Synonyms
    Copg, D6Ertd71e, D6Wsu16e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858696
    NCBI Gene: 54161
Location & Maps
more
  • Sequence Map
    Chr6:87887814-87913595 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25782 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    COPG1, coatomer protein complex subunit gamma 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    COPG1, coatomer protein complex subunit gamma 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    COPG
  • Links
    NCBI Gene ID: 22820
    neXtProt AC: NX_Q9Y678

  • Chr Location
    3q21.3; chr3:129249575-129277773 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    63
  • Gene trapped
    60
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Copg1
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022960 VEGA Gene Model | MGI Sequence Detail 25782 C57BL/6J ±  kb
transcript OTTMUST00000055237 VEGA | MGI Sequence Detail 4140 Not Applicable  
polypeptide OTTMUSP00000026425 VEGA | MGI Sequence Detail 874 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    78 from dbSNP Build 137
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005737 coatomer subunit gamma
  • PDB
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR015873 Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain
    IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
    IPR009028 Coatomer/calthrin adaptor appendage, C-terminal subdomain
    IPR013041 Coatomer/clathrin adaptor appendage, Ig-like subdomain
    IPR017106 Coatomer gamma subunit
    IPR013040 Coatomer, gamma subunit, appendage, Ig-like subdomain
    IPR032154 Coatomer subunit gamma, C-terminal
Molecular
Reagents
less
  • All nucleic 339
    cDNA 336
    Primer pair 3

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-34156, MGI:106462, MGI:1098809, MGI:2141561, MGI:3036293
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:221387 Liu L, et al., Pre-synaptic localization of the gamma-secretase-inhibiting protein p24alpha2 in the mammalian brain. J Neurochem. 2015 May;133(3):422-31

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory