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B4galt2 Gene Detail
Summary
  • Symbol
    B4galt2
  • Name
    UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858493
    NCBI Gene: 53418
  • Gene Overview
    MyGene.info: B4GALT2
Location & Maps
more
  • Sequence Map
    Chr4:117869260-117883487 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14228 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.70 cM, cytoband D1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    B4GALT2, beta-1,4-galactosyltransferase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    B4GALT2, beta-1,4-galactosyltransferase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    B4Gal-T2, B4Gal-T3, beta4Gal-T2
  • Links
    NCBI Gene ID: 8704
    neXtProt AC: NX_O60909

  • Chr Location
    1p34-p33; chr1:43979202-43991171 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    2 images
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving B4galt2
  • Incidental Mutations
Mice homozygous for a null allele exhibit decreased brain weight, ectopic Purkinje cells in the cerebellum, and impaired spatial learning and coordination.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008664 VEGA Gene Model | MGI Sequence Detail 14228 C57BL/6J ±  kb
transcript OTTMUST00000090020 VEGA | MGI Sequence Detail 4093 Not Applicable  
polypeptide OTTMUSP00000049282 VEGA | MGI Sequence Detail 369 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    68 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 48
    Genomic 1
    cDNA 45
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:67774 Nakamura N, et al., Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development. J Neurochem. 2001 Jan;76(1):29-38
  • Latest
    J:150715 Malcuit C, et al., Identification of novel oocyte and granulosa cell markers. Gene Expr Patterns. 2009 Jun 16;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory