B4galt2
Gene Detail

Symbol Name ID

B4galt2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 MGI:1858493

Feature Type

protein coding gene

Genetic Map

Chromosome 4

53.70 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr4:117869260-117883487 bp, - strand From VEGA annotation of GRCm38   14228 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2804  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: beta-1,4-galactosyltransferase, B4GalT1-6 types
Gene Tree: B4galt2

Human homologs

Human Homolog		B4GALT2, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
NCBI Gene ID		8704
neXtProt AC		NX_O60909
Human Synonyms		B4Gal-T2, B4Gal-T3, beta4Gal-T2
Human Chr (Location)		1p34-p33; chr1:44444874-44456843 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Mice homozygous for a null allele exhibit decreased brain weight, ectopic Purkinje cells in the cerebellum, and impaired spatial learning and coordination.

 

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	carbohydrate metabolic process
Component	Golgi apparatus, integral to membrane, ...
Function	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, lactose synthase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (142)    Tissues (130)    Images (11)
Theiler Stages: 1, 2, 3, 5, 19, 22, 25, 28

Assay Type	Results
RNA in situ	115
Northern blot	18
RT-PCR	9

cDNA source data(46)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(49) Genomic(1) cDNA(46) Primer pair(2)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000008664 (Evidence)
Ensembl Gene Model	ENSMUSG00000028541 (Evidence)
Entrez Gene	53418 (Evidence)
UniGene	123843
DFCI	TC1579894
EC	2.4.1.-, 2.4.1.22, 2.4.1.38, 2.4.1.90
Consensus CDS Project	CCDS18539.1
International Mouse Knockout Project Status	B4galt2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000008664	VEGA Gene Model | MGI Sequence Detail	14228	C57BL/6J
transcript	OTTMUST00000090020	VEGA | MGI Sequence Detail	4093	Not Applicable
polypeptide	OTTMUSP00000049282	VEGA | MGI Sequence Detail	369	Not Applicable

All sequences(53) RefSeq(5) UniProt(5)

Polymorphisms

SNPs(23 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003859	Galactosyltransferase, metazoa
Protein Ontology	PR:000004606	beta-1,4-galactosyltransferase 2

References

(Earliest) J:67774 Nakamura N, et al., Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development. J Neurochem. 2001 Jan;76(1):29-38
(Latest) J:150715 Malcuit C, et al., Identification of novel oocyte and granulosa cell markers. Gene Expr Patterns. 2009 Jun 16;
All references(30)