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B4galt2
Gene Detail
Symbol

Name
ID
B4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
MGI:1858493
Feature Type
protein coding gene
Genetic Map
Chromosome 4
53.70 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:117869260-117883487 bp, - strand
From VEGA annotation of GRCm38

  14228 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2804  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: B4GALT2
Protein SuperFamily: beta-1,4-galactosyltransferase, B4GalT1-6 types
Gene Tree: B4galt2

Human
homologs
B4GALT2, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8704
neXtProt AC: NX_O60909

Human Synonyms: B4Gal-T2, B4Gal-T3, beta4Gal-T2

Human Chr (Location): 1p34-p33; chr1:43979202-43991171 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Genomic Mutations involving B4galt2 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null allele exhibit decreased brain weight, ectopic Purkinje cells in the cerebellum, and impaired spatial learning and coordination.
 
Interactions
B4galt2 interacts with 307 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (140)    Tissues (129)    Images (11)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 115
Northern blot 18
RT-PCR 7
cDNA source data(45)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase b4galt2    NEW 
Molecular
reagents
All nucleic(48) Genomic(1) cDNA(45) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000008664 (Evidence)
Ensembl Gene Model ENSMUSG00000028541 (Evidence)
Entrez Gene 53418 (Evidence)
UniGene 123843
DFCI TC1579894
EC 2.4.1.-, 2.4.1.38, 2.4.1.22, 2.4.1.90
Consensus CDS Project CCDS18539.1
International Mouse Phenotyping Consortium Status B4galt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008664 VEGA Gene Model | MGI Sequence Detail 14228 C57BL/6J ±  kb
transcript OTTMUST00000090020 VEGA | MGI Sequence Detail 4093 Not Applicable 
polypeptide OTTMUSP00000049282 VEGA | MGI Sequence Detail 369 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(10) UniProt(5)
Polymorphisms
SNPs within 2kb(68 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003859 Galactosyltransferase, metazoa
Protein Ontology PR:000004606 beta-1,4-galactosyltransferase 2
References
(Earliest) J:67774 Nakamura N, et al., Differential gene expression of beta-1,4-galactosyltransferases I, II and V during mouse brain development. J Neurochem. 2001 Jan;76(1):29-38
(Latest) J:150715 Malcuit C, et al., Identification of novel oocyte and granulosa cell markers. Gene Expr Patterns. 2009 Jun 16;
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory