About   Help   FAQ
Scarf2 Gene Detail
Summary
  • Symbol
    Scarf2
  • Name
    scavenger receptor class F, member 2
  • Synonyms
    Srec2, SREC-II
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858430
    NCBI Gene: 224024
Location & Maps
more
  • Sequence Map
    Chr16:17797282-17808287 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11006 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 11.03 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SCARF2, scavenger receptor class F member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SCARF2, scavenger receptor class F member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NSR1, SREC2, SREC-II, SRECRP-1, VDEGS
  • Links
    NCBI Gene ID: 91179
    neXtProt AC: NX_Q96GP6

  • Chr Location
    22q11.21; chr22:20424584-20437859 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 17817
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SCARF2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human SCARF2 associations

Human Disease Mouse Models
       Van Den Ende-Gupta Syndrome; VDEGS   OMIM: 600920
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000012017 Ensembl Gene Model | MGI Sequence Detail 11006 C57BL/6J ±  kb
transcript ENSMUST00000012161 Ensembl | MGI Sequence Detail 3302 Not Applicable  
polypeptide ENSMUSP00000012161 Ensembl | MGI Sequence Detail 833 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    2 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    Genomic 2
    cDNA 65

    Microarray probesets 7
Other
Accession IDs
less
MGI:1858437, MGI:1858438, MGI:2146384
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:60871 Lund J, et al., Comparative sequence analysis of 634 kb of the mouse chromosome 16 region of conserved synteny with the human velocardiofacial syndrome region on chromosome 22q11.2. Genomics. 2000 Feb 1;63(3):374-83
  • Latest
    J:236397 Bildsoe H, et al., Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance. Dev Biol. 2016 Oct 1;418(1):189-203

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/29/2016
MGI 6.06
The Jackson Laboratory