Mcrs1
Gene Detail

Symbol Name ID

Mcrs1 microspherule protein 1 MGI:1858420

Synonyms

C78274, ICP22BP, MSP58, P78

Feature Type

protein coding gene

Genetic Map

Chromosome 15

56.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr15:99242818-99251961 bp, - strand From Ensembl annotation of GRCm38   9144 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4622  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mcrs1

Human homologs

Human Homolog		MCRS1, microspherule protein 1
NCBI Gene ID		10445
neXtProt AC		NX_Q96EZ8
Human Synonyms		ICP22BP, INO80Q, MCRS2, MSP58, P78
Human Chr (Location)		12q13.12; chr12:49952085-49961911 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(34) : Targeted(1) Gene trapped(33)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	chromatin modification, DNA recombination, ...
Component	histone acetyltransferase complex, Ino80 complex, ...
Function	histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (18)    Tissues (17)    Images (3)
Theiler Stages: 17, 23

Assay Type	Results
RNA in situ	18

cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) cDNA(10)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000037570 (Evidence)
Entrez Gene	51812 (Evidence)
DFCI	TC1572306
DoTS	DT.101146428, DT.101383103, DT.110801609, DT.110831596, DT.535352, DT.99864440
Consensus CDS Project	CCDS37199.1, CCDS49728.1
International Mouse Knockout Project Status	Mcrs1

Sequences

Length	Strain/Species
genomic	ENSMUSG00000037570	Ensembl Gene Model | MGI Sequence Detail	9144	C57BL/6J
transcript	ENSMUST00000041190	Ensembl | MGI Sequence Detail	1915	Not Applicable
polypeptide	ENSMUSP00000043901	Ensembl | MGI Sequence Detail	462	Not Applicable

All sequences(41) RefSeq(4) UniProt(3)

Polymorphisms

SNPs(52 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000253	Forkhead-associated (FHA) domain
InterPro	IPR025999	Microspherule protein, N-terminal domain
InterPro	IPR008984	SMAD/FHA domain
Protein Ontology	PR:000010256	microspherule protein 1

References

(Earliest) J:61845 Ren Y, et al., The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120. Eur J Biochem. 1998 May 1;253(3):734-42
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(29)

Other accession IDs

MGI:2146281