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Timm23
Gene Detail
 Symbol
Name
ID
Timm23
translocase of inner mitochondrial membrane 23
MGI:1858317
Synonyms MGC:46821, Tim23
Feature Type protein coding gene
Genetic Map
Chromosome 14
19.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr14:32180162-32201898 bp, - strand
From VEGA annotation of GRCm38

  21737 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9651  Vertebrate Homology Class
1 human; 1 mouse; 3 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Timm23

Human
homologs
Human Homolog TIMM23, translocase of inner mitochondrial membrane 23 homolog (yeast)
NCBI Gene ID 100287932
neXtProt AC  NX_O14925
Human Synonyms  TIM23
Human Chr (Location)  chr10:45972453-46003742 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(38) : Gene trapped(36) Targeted(2)
Incidental mutations (data from APF )
 
Mice homozygous for a gene trapped allele die prior to E3.5. Mice heterogygous for this allele exhibit background sensitive premature aging and increased mortality.
 
Interactions
Timm23 interacts with 97 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Component integral component of mitochondrial inner membrane, mitochondrial inner membrane, ...
Function enzyme binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (77)    Tissues (14)    Images (23)
Theiler Stages: 16, 22, 23, 28
Assay TypeResults
RNA in situ 70
In situ reporter (knock in) 3
Western blot 4
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) Genomic(1) cDNA(9)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000036490 (Evidence)
Ensembl Gene ModelENSMUSG00000013701 (Evidence)
Entrez Gene53600 (Evidence)
DFCITC1572508, TC1749669
NIA Mouse Gene IndexU040944, U062919, U129548, U135210, U349673
Consensus CDS ProjectCCDS36864.1
International Mouse Knockout Project StatusTimm23
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036490 VEGA Gene Model | MGI Sequence Detail 21737 C57BL/6J ±  kb
transcript OTTMUST00000093545 VEGA | MGI Sequence Detail 1173 Not Applicable 
polypeptide OTTMUSP00000051926 VEGA | MGI Sequence Detail 209 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2)
Polymorphisms SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000016347 mitochondrial import inner membrane translocase subunit Tim23
References (Earliest) J:63697 Underhill DA, et al., Transcription mapping and expression analysis of candidate genes in the vicinity of the mouse Loop-tail mutation. Mamm Genome. 2000 Aug;11(8):633-8
(Latest) J:179027 Engl G, et al., Alterations in expression levels of deafness dystonia protein 1 affect mitochondrial morphology. Hum Mol Genet. 2012 Jan 15;21(2):287-99
All references(43)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory