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Gal3st1
Gene Detail
 Symbol
Name
ID
Gal3st1
galactose-3-O-sulfotransferase 1
MGI:1858277
Synonyms 3'-phosphoadenylylsulfate-galactosylceramide 3'-sulfotransferase, Cst, galactosylceramide sulfotransferase, GalCer sulfotransferase, Gcst
Feature Type protein coding gene
Genetic Map
Chromosome 11
2.81 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:3983636-3999326 bp, + strand
From VEGA annotation of GRCm38

  15691 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3574  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Gal3st1

Human
homologs
Human Homolog GAL3ST1, galactose-3-O-sulfotransferase 1
NCBI Gene ID 9514
neXtProt AC  NX_Q99999
Human Synonyms  CST
Human Chr (Location)  22q12.2; chr22:30554635-30574578 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a targeted null mutation exhibit hindlimb weakness and progressive ataxia beginning at six weeks of age. Homozygous males exhibit sterility with a block in spermatogenesis prior to the first meiotic division.
 
Interactions
Gal3st1 interacts with 27 markers (Mir322, Mir344g, Mir377, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process biosynthetic process, galactosylceramide biosynthetic process, ...
Component Golgi apparatus, Golgi membrane, ...
Function galactosylceramide sulfotransferase activity, transferase activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (111)    Tissues (100)    Images (10)
Theiler Stages: 20, 22, 23, 24, 26, 28
Assay TypeResults
RNA in situ 104
RT-PCR 7
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000005048 (Evidence)
Ensembl Gene ModelENSMUSG00000049721 (Evidence)
Entrez Gene53897 (Evidence)
UniGene103414
DFCITC1586461, TC1595445
DoTSDT.55283267, DT.91336591, DT.97360687
NIA Mouse Gene IndexU012261
EC2.8.2.11
Consensus CDS ProjectCCDS24373.1
International Mouse Knockout Project StatusGal3st1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005048 VEGA Gene Model | MGI Sequence Detail 15691 C57BL/6J ±  kb
transcript OTTMUST00000011236 VEGA | MGI Sequence Detail 1749 Not Applicable 
polypeptide OTTMUSP00000005240 VEGA | MGI Sequence Detail 423 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(61 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009729 Galactose-3-O-sulfotransferase
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000007807 galactosylceramide sulfotransferase
References (Earliest) J:61464 Hirahara Y, et al., cDNA cloning, genomic cloning, and tissue-specific regulation of mouse cerebroside sulfotransferase. Eur J Biochem. 2000 Apr;267(7):1909-17
(Latest) J:197393 Stettner P, et al., Sulfatides are required for renal adaptation to chronic metabolic acidosis. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9998-10003
All references(45)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory