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Gal3st1
Gene Detail
Symbol

Name
ID
Gal3st1
galactose-3-O-sulfotransferase 1
MGI:1858277
Synonyms
3'-phosphoadenylylsulfate-galactosylceramide 3'-sulfotransferase, Cst, galactosylceramide sulfotransferase, GalCer sulfotransferase, Gcst
Feature Type
protein coding gene
Genetic Map
Chromosome 11
2.81 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:3983636-3999326 bp, + strand
From VEGA annotation of GRCm38

  15691 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3574  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GAL3ST1
Gene Tree: Gal3st1

Human
homologs
GAL3ST1, galactose-3-O-sulfotransferase 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9514
neXtProt AC: NX_Q99999

Human Synonyms: CST

Human Chr (Location): 22q12.2; chr22:30554635-30574588 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygotes for a targeted null mutation exhibit hindlimb weakness and progressive ataxia beginning at six weeks of age. Homozygous males exhibit sterility with a block in spermatogenesis prior to the first meiotic division.
 
Interactions
Gal3st1 interacts with 27 markers (Mir322, Mir344g, Mir377, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (111)    Tissues (101)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 104
RT-PCR 7
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gal3st1 ; ZFIN gal3st1a    NEW 
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000005048 (Evidence)
Ensembl Gene Model ENSMUSG00000049721 (Evidence)
Entrez Gene 53897 (Evidence)
UniGene 103414
DFCI TC1586461, TC1595445
DoTS DT.55283267, DT.97360687, DT.91336591
NIA Mouse Gene Index U012261
EC 2.8.2.11
Consensus CDS Project CCDS24373.1
International Mouse Phenotyping Consortium Status Gal3st1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005048 VEGA Gene Model | MGI Sequence Detail 15691 C57BL/6J ±  kb
transcript OTTMUST00000011236 VEGA | MGI Sequence Detail 1749 Not Applicable 
polypeptide OTTMUSP00000005240 VEGA | MGI Sequence Detail 423 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(10) UniProt(1)
Polymorphisms
SNPs within 2kb(61 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009729 Galactose-3-O-sulfotransferase
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000007807 galactosylceramide sulfotransferase
References
(Earliest) J:61464 Hirahara Y, et al., cDNA cloning, genomic cloning, and tissue-specific regulation of mouse cerebroside sulfotransferase. Eur J Biochem. 2000 Apr;267(7):1909-17
(Latest) J:216599 Marsching C, et al., Quantitative imaging mass spectrometry of renal sulfatides: validation by classical mass spectrometric methods. J Lipid Res. 2014 Nov;55(11):2343-53
All references(45)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory