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Mtmr1 Gene Detail
Summary
  • Symbol
    Mtmr1
  • Name
    myotubularin related protein 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858271
    NCBI Gene: 53332
  • Gene Overview
    MyGene.info: MTMR1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:71364760-71419196 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 36.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    267 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858271
protein coding gene ChrX:71364760-71419196 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035782
protein coding gene ChrX:67011234-67068975 (+)
A/J MGP_AJ_G0035765
protein coding gene ChrX:67242109-67300660 (+)
AKR/J MGP_AKRJ_G0035687
protein coding gene ChrX:69047595-69101736 (+)
BALB/cJ MGP_BALBcJ_G0035752
protein coding gene ChrX:66332296-66386858 (+)
C3H/HeJ MGP_C3HHeJ_G0035455
protein coding gene ChrX:67528077-67587402 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036282
protein coding gene ChrX:69055170-69109409 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033130
protein coding gene ChrX:66500588-66560554 (+)
CAST/EiJ MGP_CASTEiJ_G0034747
protein coding gene ChrX:52914100-52975497 (+)
CBA/J MGP_CBAJ_G0035430
protein coding gene ChrX:70982574-71037191 (+)
DBA/2J MGP_DBA2J_G0035583
protein coding gene ChrX:66755611-66809973 (+)
FVB/NJ MGP_FVBNJ_G0035534
protein coding gene ChrX:66120446-66176946 (+)
LP/J MGP_LPJ_G0035672
protein coding gene ChrX:67853569-67910982 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035569
protein coding gene ChrX:73506725-73562484 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036303
protein coding gene ChrX:66871412-66929315 (+)
PWK/PhJ MGP_PWKPhJ_G0034447
protein coding gene ChrX:50961434-51017470 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034283
protein coding gene ChrX:53810588-53874400 (+)
WSB/EiJ MGP_WSBEiJ_G0034889
protein coding gene ChrX:66204469-66260320 (+)



Homology
more
  • Human Ortholog
    MTMR1, myotubularin related protein 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MTMR1, myotubularin related protein 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 8776
    neXtProt AC: NX_Q13613
    UniProt: Q13613

  • Chr Location
    Xq28; chrX:150692997-150765103 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2840
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MTMR1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Female mice homozygous and male mice hemizygous for a gene disruption display normal morphology, clinical chemistry, hematology, and behavior.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 53332 NCBI Gene Model | MGI Sequence Detail 54437 C57BL/6J ±  kb
transcript NM_001313702 RefSeq | MGI Sequence Detail 4754 C57BL/6  
polypeptide Q9Z2C4 UniProt | EBI | MGI Sequence Detail 669 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 74
    cDNA 70
    Primer pair 4

    Microarray probesets 6
Other
Accession IDs
less
MGI:2147990
References
more
  • Summaries
    All 29
    Developmental Gene Expression 7
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:62647 Laporte J, et al., Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human. Hum Mol Genet. 1998 Oct;7(11):1703-12
  • Latest
    J:204566 Gendrel AV, et al., Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory