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Mtmr1
Gene Detail
 Symbol
Name
ID
Mtmr1
myotubularin related protein 1
MGI:1858271
Feature Type protein coding gene
Genetic Map
Chromosome X
36.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:71364760-71419196 bp, + strand
From VEGA annotation of GRCm38

  54437 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2840  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Mtmr1

Human
homologs
Human Homolog MTMR1, myotubularin related protein 1
NCBI Gene ID 8776
neXtProt AC  NX_Q13613
Human Chr (Location)  Xq28; chrX:150692968-150765102 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Female mice homozygous and male mice hemizygous for a gene disruption display normal morphology, clinical chemistry, hematology, and behavior.
 
Interactions
Mtmr1 interacts with 337 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (32 annotations)
Process dephosphorylation
Component cytoplasm, membrane, ...
Function 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (215)    Tissues (178)    Images (59)
Theiler Stages: 21, 22, 23, 25, 26, 28
Assay TypeResults
RNA in situ 94
In situ reporter (knock in) 59
RT-PCR 62
cDNA source data(69)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(73) cDNA(69) Primer pair(4)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000017893 (Evidence)
Ensembl Gene ModelENSMUSG00000015214 (Evidence)
Entrez Gene53332 (Evidence)
UniGene219672
DFCITC1576947, TC1607710, TC1676673
DoTSDT.101149070, DT.101736049, DT.91337738, DT.91573366, DT.94199152, DT.99841317
NIA Mouse Gene IndexU019916
EC3.1.3.-
Consensus CDS ProjectCCDS30178.1
International Mouse Knockout Project StatusMtmr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017893 VEGA Gene Model | MGI Sequence Detail 54437 C57BL/6J ±  kb
transcript OTTMUST00000043273 VEGA | MGI Sequence Detail 4640 Not Applicable 
polypeptide OTTMUSP00000019453 VEGA | MGI Sequence Detail 671 Not Applicable 

For the selected sequences
All sequences(94) RefSeq(22) UniProt(11)
Polymorphisms SNPs within 2kb(269 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004182 GRAM
InterPro IPR010569 Myotubularin-related
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR000387 Protein-tyrosine/Dual specificity phosphatase
InterPro IPR016130 Protein-tyrosine phosphatase, active site
Protein Ontology PR:000010731 myotubularin-related protein 1
References (Earliest) J:62647 Laporte J, et al., Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human. Hum Mol Genet. 1998 Oct;7(11):1703-12
(Latest) J:185949 Licatalosi DD, et al., Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Genes Dev. 2012 Jul 15;26(14):1626-42
All references(32)
Other
accession IDs
MGI:2147990

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory