Slc7a10
Gene Detail

Symbol Name ID

Slc7a10 solute carrier family 7 (cationic amino acid transporter, y+ system), member 10 MGI:1858261

Synonyms

Asc-1, D7Bwg0847e

Feature Type

protein coding gene

Genetic Map

Chromosome 7

21.13 cM, cytoband B1-B5
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr7:35186385-35204898 bp, + strand From VEGA annotation of GRCm38   18514 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:56767  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: amino acid transporter
Gene Tree: Slc7a10

Human homologs

Human Homolog		SLC7A10, solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
NCBI Gene ID		56301
neXtProt AC		NX_Q9NS82
Human Synonyms		asc-1, HASC-1
Human Chr (Location)		19q13.1; chr19:33699570-33716756 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

A targeted mutation of this gene results in mice that develop tremors, ataxia and seizures.

 

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	amino acid transmembrane transport, amino acid transport, ...
Component	dendrite, integral to membrane, ...
Function	amino acid transmembrane transporter activity, neutral amino acid transmembrane transporter activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (116)    Tissues (13)    Images (22)
Theiler Stages: 23

Assay Type	Results
RNA in situ	116

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(6) cDNA(4) Primer pair(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000027210 (Evidence)
Ensembl Gene Model	ENSMUSG00000030495 (Evidence)
Entrez Gene	53896 (Evidence)
NIA Mouse Gene Index	U007966
Consensus CDS Project	CCDS21146.1
International Mouse Knockout Project Status	Slc7a10

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027210	VEGA Gene Model | MGI Sequence Detail	18514	C57BL/6J
transcript	OTTMUST00000067287	VEGA | MGI Sequence Detail	1949	Not Applicable
polypeptide	OTTMUSP00000033827	VEGA | MGI Sequence Detail	530	Not Applicable

All sequences(43) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(98 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002293	Amino acid/polyamine transporter I
Protein Ontology	PR:000015195	asc-type amino acid transporter 1

References

(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Other accession IDs

MGD-MRK-34148, MGI:106454, MGI:2142097