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Slc7a10
Gene Detail
 Symbol
Name
ID
Slc7a10
solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
MGI:1858261
Synonyms Asc-1, D7Bwg0847e
Feature Type protein coding gene
Genetic Map
Chromosome 7
21.13 cM, cytoband B1-B5
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr7:35186385-35204898 bp, + strand
From VEGA annotation of GRCm38

  18514 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56767  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: amino acid transporter
Gene Tree: Slc7a10

Human
homologs
Human Homolog SLC7A10, solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
NCBI Gene ID 56301
neXtProt AC  NX_Q9NS82
Human Synonyms  asc-1, HASC-1
Human Chr (Location)  19q13.1; chr19:33208664-33225850 (-)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
 
A targeted mutation of this gene results in mice that develop tremors, ataxia and seizures.
 
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process amino acid transmembrane transport, amino acid transport, ...
Component dendrite, integral component of membrane, ...
Function amino acid transmembrane transporter activity, neutral amino acid transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (138)    Tissues (35)    Images (23)
Theiler Stages: 23, 28
Assay TypeResults
RNA in situ 138
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(4) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027210 (Evidence)
Ensembl Gene ModelENSMUSG00000030495 (Evidence)
Entrez Gene53896 (Evidence)
NIA Mouse Gene IndexU007966
Consensus CDS ProjectCCDS21146.1
International Mouse Knockout Project StatusSlc7a10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027210 VEGA Gene Model | MGI Sequence Detail 18514 C57BL/6J ±  kb
transcript OTTMUST00000067287 VEGA | MGI Sequence Detail 1949 Not Applicable 
polypeptide OTTMUSP00000033827 VEGA | MGI Sequence Detail 530 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(10) UniProt(6)
Polymorphisms SNPs within 2kb(126 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002293 Amino acid/polyamine transporter I
Protein Ontology PR:000015195 asc-type amino acid transporter 1
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGD-MRK-34148, MGI:106454, MGI:2142097

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory