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Eif3g
Gene Detail
Symbol

Name
ID
Eif3g
eukaryotic translation initiation factor 3, subunit G
MGI:1858258
Synonyms
44kDa, D0Jmb4, Eif3s4, p44, TU-189B2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
7.66 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:20894349-20898590 bp, - strand
From NCBI annotation of GRCm38

  4242 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2784  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: EIF3G
Protein SuperFamily: translation initiation factor 3, RNA-binding subunit
Gene Tree: Eif3g

Human
homologs
EIF3G, eukaryotic translation initiation factor 3, subunit G
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 8666
neXtProt AC: NX_O75821

Human Synonyms: eIF3-delta, EIF3-P42, eIF3-p44, EIF3S4

Human Chr (Location): 19p13.2; chr19:10115014-10119923 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(7) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Eif3g interacts with 13 markers (Mir127, Mir208b, Mir328, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process translation, translational initiation
Component cytoplasm, eukaryotic translation initiation factor 3 complex, ...
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
cDNA source data(157)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase eif3s4 ; ZFIN eif3g    NEW 
Molecular
reagents
All nucleic(157) cDNA(157)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000070319 (Evidence)
Entrez Gene 53356 (Evidence)
UniGene 427309
DFCI TC1574222
DoTS DT.495160
NIA Mouse Gene Index U030562
Consensus CDS Project CCDS40547.1
International Mouse Phenotyping Consortium Status Eif3g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 53356 NCBI Gene Model | MGI Sequence Detail 4242 C57BL/6J ±  kb
transcript NM_016876 RefSeq | MGI Sequence Detail 1068 C57BL/6 
polypeptide Q9Z1D1 UniProt | EBI | MGI Sequence Detail 320 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(53 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017334 Eukaryotic translation initiation factor 3 subunit G
InterPro IPR024675 Eukaryotic translation initiation factor 3 subunit G, N-terminal
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000006979 eukaryotic translation initiation factor 3 subunit G
Graphical View of Protein Domain Structure
References
(Earliest) J:25193 Gordon HM, et al., Tumor necrosis factor induces genes involved in inflammation, cellular and tissue repair, and metabolism in murine fibroblasts. J Immunol. 1992 Jun 15;148(12):4021-7
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:1206577

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory