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Mpp2 Gene Detail
Summary
  • Symbol
    Mpp2
  • Name
    membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
  • Synonyms
    D11Bwg0652e, Dlg2, Dlgh2, Pals4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858257
    NCBI Gene: 50997
  • Gene Overview
    MyGene.info: MPP2
Location & Maps
more
  • Sequence Map
    Chr11:102057015-102088515 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31501 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 65.48 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MPP2, membrane palmitoylated protein 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MPP2, membrane palmitoylated protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DLG2
  • Links
    NCBI Gene ID: 4355
    neXtProt AC: NX_Q14168
    UniProt: Q14168

  • Chr Location
    17q21.31; chr17:43875357-43909711 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3920
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: MPP2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002315 VEGA Gene Model | MGI Sequence Detail 31501 C57BL/6J ±  kb
transcript OTTMUST00000039190 VEGA | MGI Sequence Detail 3577 Not Applicable  
polypeptide OTTMUSP00000017504 VEGA | MGI Sequence Detail 569 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    138 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 34
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-34058, MGI:106365
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:37257 Elder B, et al., cDNA sequence and genomic structure of the murine p55 (Mpp1) gene. Genomics. 1996 Dec 1;38(2):231-4
  • Latest
    J:231015 Kim G, et al., Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function. Elife. 2016;5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory