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Caprin1
Gene Detail
Symbol

Name
ID
Caprin1
cell cycle associated protein 1
MGI:1858234
Synonyms
caprin-1, Gpiap1, MMGPIP137, RNG105
Feature Type
protein coding gene
Genetic Map
Chromosome 2
54.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:103762941-103797649 bp, - strand
From VEGA annotation of GRCm38

  34709 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4310  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Caprin1

Human
homologs
Human Homolog CAPRIN1, cell cycle associated protein 1
NCBI Gene ID 4076
neXtProt AC  NX_Q14444
Human Synonyms  GPIAP1, GPIP137, GRIP137, M11S1, p137GPI, RNG105
Human Chr (Location)  11p13; chr11:34051683-34102610 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(75) : Gene trapped(69) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased fetal size, bent posture, cyanosis, respiratory failure, and neonatal lethality with impaired neuronal network development and reduced dendritic localization of sodium potassium ATPase subunit isoform mRNAs.
 
Interactions
Caprin1 interacts with 455 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell differentiation, negative regulation of translation, ...
Component cell projection, cytoplasm, ...
Function poly(A) RNA binding, RNA binding
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (49)    Tissues (46)    Images (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 49
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000014878 (Evidence)
Ensembl Gene ModelENSMUSG00000027184 (Evidence)
Entrez Gene53872 (Evidence)
DFCITC1573855, TC1649761, TC1714539, TC1743440
DoTSDT.101398182, DT.101248199, DT.487907, DT.110716117, DT.496489, DT.496492, DT.110716070, DT.103580237, DT.94378283, DT.94378253, DT.91436397, DT.97387905, DT.97387908
NIA Mouse Gene IndexU379713, U102469, U043838
Consensus CDS ProjectCCDS16481.1
International Mouse Knockout Project StatusCaprin1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014878 VEGA Gene Model | MGI Sequence Detail 34709 C57BL/6J ±  kb
transcript OTTMUST00000035357 VEGA | MGI Sequence Detail 6169 Not Applicable 
polypeptide OTTMUSP00000015808 VEGA | MGI Sequence Detail 707 Not Applicable 

For the selected sequences
All sequences(137) RefSeq(12) UniProt(17)
Polymorphisms
SNPs within 2kb(127 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022070 Cytoplasmic activation/proliferation-associated protein-1 C term
Protein Ontology PR:000005024 caprin-1
References
(Earliest) J:31588 Gessler M, et al., The gene encoding the GPI-anchored membrane protein p137GPI (M11S1) maps to human chromosome 11p13 and is highly conserved in the mouse. Genomics. 1996 Feb 15;32(1):169-70
(Latest) J:202415 Sabile AA, et al., Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice. Biochim Biophys Acta. 2013 Aug;1832(8):1173-82
All references(47)
Other
accession IDs
MGI:2139127

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory