About   Help   FAQ
Caprin1
Gene Detail
Symbol

Name
ID
Caprin1
cell cycle associated protein 1
MGI:1858234
Synonyms
caprin-1, Gpiap1, MMGPIP137, RNG105
Feature Type
protein coding gene
Genetic Map
Chromosome 2
54.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:103762941-103797649 bp, - strand
From VEGA annotation of GRCm38

  34709 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4310  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: CAPRIN1
Gene Tree: Caprin1

Human
homologs
CAPRIN1, cell cycle associated protein 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 4076
neXtProt AC: NX_Q14444

Human Synonyms: GPIAP1, GPIP137, GRIP137, M11S1, p137GPI, RNG105

Human Chr (Location): 11p13; chr11:34051617-34102610 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(75) : Gene trapped(69) Targeted(6)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit decreased fetal size, bent posture, cyanosis, respiratory failure, and neonatal lethality with impaired neuronal network development and reduced dendritic localization of sodium potassium ATPase subunit isoform mRNAs.
 
Interactions
Caprin1 interacts with 454 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell differentiation, negative regulation of translation, ...
Component cell projection, cytoplasm, ...
Function poly(A) RNA binding, RNA binding
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (49)    Tissues (46)    Images (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 49
cDNA source data(22)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA CAPRIN1 ; Xenbase caprin1 ; ZFIN caprin1a    NEW 
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000014878 (Evidence)
Ensembl Gene Model ENSMUSG00000027184 (Evidence)
Entrez Gene 53872 (Evidence)
DFCI TC1573855, TC1743440, TC1714539, TC1649761
DoTS DT.101248199, DT.487907, DT.110716117, DT.110716070, DT.103580237, DT.101398182, DT.97387908, DT.496489, DT.97387905, DT.91436397, DT.496492, DT.94378283, DT.94378253
NIA Mouse Gene Index U379713, U102469, U043838
Consensus CDS Project CCDS16481.1
International Mouse Phenotyping Consortium Status Caprin1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014878 VEGA Gene Model | MGI Sequence Detail 34709 C57BL/6J ±  kb
transcript OTTMUST00000035357 VEGA | MGI Sequence Detail 6169 Not Applicable 
polypeptide OTTMUSP00000015808 VEGA | MGI Sequence Detail 707 Not Applicable 

For the selected sequences
All sequences(130) RefSeq(12) UniProt(9)
Polymorphisms
SNPs within 2kb(127 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022070 Cytoplasmic activation/proliferation-associated protein-1 C term
Protein Ontology PR:000005024 caprin-1
References
(Earliest) J:31588 Gessler M, et al., The gene encoding the GPI-anchored membrane protein p137GPI (M11S1) maps to human chromosome 11p13 and is highly conserved in the mouse. Genomics. 1996 Feb 15;32(1):169-70
(Latest) J:202415 Sabile AA, et al., Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice. Biochim Biophys Acta. 2013 Aug;1832(8):1173-82
All references(46)
Other
accession IDs
MGI:2139127

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory