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Sart3
Gene Detail
 Symbol
Name
ID
Sart3
squamous cell carcinoma antigen recognized by T cells 3
MGI:1858230
Feature Type protein coding gene
Genetic Map
Chromosome 5
55.55 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:113742446-113771649 bp, - strand
From NCBI annotation of GRCm38

  29204 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40977  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sart3

Human
homologs
Human Homolog SART3, squamous cell carcinoma antigen recognized by T cells 3
NCBI Gene ID 9733
neXtProt AC  NX_Q15020
Human Synonyms  DSAP1, P100, p110, p110(nrb), RP11-13G14, TIP110
Human Chr (Location)  12q24.1; chr12:108522214-108561389 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SART3
Alleles
and
phenotypes
All alleles(11) : Gene trapped(8) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a conditional allele activated in hematopoietic cells exhibit protection against the effects of 5-FU treatment.
 
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell morphogenesis, hematopoietic stem cell proliferation, ...
Component cytoplasm, intracellular, ...
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (61)    Tissues (50)    Images (4)
Theiler Stages: 10, 18, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 20
Northern blot 39
RT-PCR 2
cDNA source data(145)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(148) cDNA(146) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000018974 (Evidence)
Entrez Gene53890 (Evidence)
UniGene29594
DFCITC1572838
DoTSDT.101399211, DT.493752, DT.94165593
NIA Mouse Gene IndexU026591
Consensus CDS ProjectCCDS19552.1
International Mouse Knockout Project StatusSart3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 53890 NCBI Gene Model | MGI Sequence Detail 29204 C57BL/6J ±  kb
transcript NM_016926 RefSeq | MGI Sequence Detail 3586 BALB/c 
polypeptide Q9JLI8 UniProt | EBI | MGI Sequence Detail 962 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(171 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008669 LSM-interacting domain
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR003107 RNA-processing protein, HAT helix
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000014462 squamous cell carcinoma antigen recognized by T-cells 3
Graphical View of Protein Domain Structure
References (Earliest) J:60863 Harada K, et al., Mouse homologue of the human SART3 gene encoding tumor-rejection antigen. Jpn J Cancer Res. 2000 Feb;91(2):239-47
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:2141094

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory