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Stx7
Gene Detail
Symbol

Name
ID
Stx7
syntaxin 7
MGI:1858210
Feature Type
protein coding gene
Genetic Map
Chromosome 10
11.45 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:24149317-24188959 bp, + strand
From Ensembl annotation of GRCm38

  39643 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37823  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: STX7
Gene Tree: Stx7

Human
homologs
STX7, syntaxin 7
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 8417
neXtProt AC: NX_O15400

Human Chr (Location): 6q23.1; chr6:132457524-132513198 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Stx7 interacts with 191 markers (Mir1b, Mir15b, Mir17, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (46 annotations)
Process intracellular protein transport, membrane fusion, ...
Component azurophil granule, early endosome, ...
Function chloride channel inhibitor activity, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (106)    Tissues (13)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 106
cDNA source data(125)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase stx7    NEW 
Molecular
reagents
All nucleic(125) cDNA(125)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000019998 (Evidence)
Entrez Gene 53331 (Evidence)
UniGene 248042
DFCI TC1572634, TC1771357
DoTS DT.110627519, DT.491416, DT.94217381, DT.97408157
NIA Mouse Gene Index U011346
PDB 1GL2
Consensus CDS Project CCDS23749.1
International Mouse Phenotyping Consortium Status Stx7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019998 Ensembl Gene Model | MGI Sequence Detail 39643 C57BL/6J ±  kb
transcript ENSMUST00000020174 Ensembl | MGI Sequence Detail 2500 Not Applicable 
polypeptide ENSMUSP00000020174 Ensembl | MGI Sequence Detail 261 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(183 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006012 Syntaxin/epimorphin, conserved site
InterPro IPR006011 Syntaxin, N-terminal domain
InterPro IPR000727 Target SNARE coiled-coil homology domain
InterPro IPR010989 t-SNARE
Protein Ontology PR:000015799 syntaxin-7
References
(Earliest) J:75403 Nakamura N, et al., Syntaxin 7 mediates endocytic trafficking to late endosomes. J Biol Chem. 2000 Mar 3;275(9):6523-9
(Latest) J:206800 Pirooz SD, et al., UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2716-21
All references(43)
Other
accession IDs
MGI:2143566, MGI:2143572, MGI:2143805

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory