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Ear7 Gene Detail
Summary
  • Symbol
    Ear7
  • Name
    eosinophil-associated, ribonuclease A family, member 7
  • Synonyms
    mR7, murine ribonuclease 7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858205
    NCBI Gene: 53873
  • Alliance
Location &
Maps
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  • Sequence Map
    Chr14:52090539-52092378 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
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  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858205
protein coding gene Chr14:52090539-52092378 (.)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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  • Other Mouse Links
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic AY324806 GenBank | ENA | DDBJ | MGI Sequence Detail 1837 C57BL/6 ±  kb
transcript NM_017385 RefSeq | MGI Sequence Detail 468 C57BL/6  
polypeptide NP_059081 RefSeq | MGI Sequence Detail 155 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001427 Pancreatic ribonuclease
    IPR023411 Ribonuclease A, active site
    IPR023412 Ribonuclease A-domain
    IPR036816 Ribonuclease A-like domain superfamily
References
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  • Summaries
    All 8
    Gene Ontology 1
  • Earliest
    J:36253 Larson KA, et al., Two highly homologous ribonuclease genes expressed in mouse eosinophils identify a larger subgroup of the mammalian ribonuclease superfamily. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12370-5
  • Latest
    J:87791 Dyer KD, et al., Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene. Mamm Genome. 2004 Mar;15(2):126-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory