Ear7
Gene Detail

Symbol Name ID

Ear7 eosinophil-associated, ribonuclease A family, member 7 MGI:1858205

Synonyms

mR7, murine ribonuclease 7

Feature Type

protein coding gene

Genetic Map

Chromosome 14
Syntenic

Mapping data(1)

Sequence Map

Chr14:51853081-51854920 bp From MGI annotation of GRCm38   1840 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	RNA metabolic process
Component	secretory granule
Function	endonuclease activity, hydrolase activity, ...

External Resources: FuncBase

Expression

External Resources: GEO  

Other database links

Entrez Gene

53873 (Evidence)

Sequences

Length	Strain/Species
genomic	AY324806	GenBank | EMBL | DDBJ | MGI Sequence Detail	1837	C57BL/6
transcript	NM_017385	RefSeq | MGI Sequence Detail	468	C57BL/6
polypeptide	NP_059081	RefSeq | MGI Sequence Detail	155	C57BL/6

All sequences(5) RefSeq(2) UniProt(1)

Protein-related information

Resource	ID	Description
InterPro	IPR001427	Ribonuclease A
InterPro	IPR023411	Ribonuclease A, active site
InterPro	IPR023412	Ribonuclease A-domain

References

(Earliest) J:36253 Larson KA, et al., Two highly homologous ribonuclease genes expressed in mouse eosinophils identify a larger subgroup of the mammalian ribonuclease superfamily. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12370-5
(Latest) J:87791 Dyer KD, et al., Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene. Mamm Genome. 2004 Mar;15(2):126-34
All references(8)